Clinical significance of metastasectomy and pathological response to pembrolizumab in mismatch repair-deficient metastatic colorectal cancer: A retrospective multi-institutional study
Yoshifumi Shimada,
Mae Nakano,
Akio Matsumoto
et al.
Abstract:Background: Metastasectomy is an important treatment to improve survival outcomes in metastatic colorectal cancer (mCRC). However, the evidence regarding the significance of metastasectomy in selected patients with tumors deficient in mismatch repair (dMMR) has been lacking. We aimed to describe the significance of metastasectomy in patients with dMMR mCRC, and the pathological complete response (pCR) rate of patients who underwent metastasectomy after pembrolizumab treatment.
Methods: This retrospective analy… Show more
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