Clinical Significance of HSCARG for Atherosclerotic Coronary Heart Disease and Reduced ROS-Oxidative Stress in in Vivo and in Vitro Models via p47phox by NF-κB Activity
Abstract:Introduction
Coronary heart disease (CHD) is a dynamic process in which there are
interactions between endothelial dysfunction, oxidative stress, and
inflammatory responses. The aim of the present study was to investigate the
function and mechanism of HSCARG in the treatment of CHD.
Methods
Male apolipoprotein E/low-density lipoprotein receptor-deficient mice were
given a high-fat diet with 21% fat and 0.15% cholesterol for the in vivo
model. Human umbilical vein endoth… Show more
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