Clinical significance of extrathyroidal extension to major vessels in papillary thyroid carcinoma

Abuduwaili, Munire; Su, Anping; Xing, Zhichao; Xia, Baoying; Wu, Zhujuan; Fei, Y.; Zhu, Jingqiang; Chen, Z.

doi:10.1007/s40618-022-01966-5

Cited by 2 publications

(1 citation statement)

References 54 publications

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“…Research [38,39] has found that extrathyroidal extension (ETE) is associated with mortality and recurrence rates in patients with PTC. Feng et al [19] demonstrated that patients with ETE were 2.144 times more likely to develop CLNM than patients without ETE and suggested that the relationship between ETE and CLNM could provide a theoretical basis for lymph node dissection in patients with PTC.…”

Section: Discussionmentioning

confidence: 99%

Untitled

2023

Horm Metab Res

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To study risk factors for central lymph node metastasis (CLNM) in papillary thyroid cancer (PTC) using the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS). We retrospectively analysed patients who underwent PTC surgery and central lymph node dissection at First People's Hospital of Foshan City. The clinical and ultrasonic data of the patients from 1150 cases were analysed by multivariate regression to evaluate the correlation between grayscale ultrasound (US) features, C-TI-RADS score, and the classification of thyroid nodules and CLNM of PTCs. The C-TIRADS score was 3.0 ± 1.0 in the CLNM group, which was higher than that in the non-CLNM group (p < 0.001). Sex (male) (OR = 1.586, 95 % CI 1.232-2.042, p < 0.001), age ( ≤ 45 years) (OR = 1.508, 95 % CI 1.184-1.919, p = 0.001), location of nodes (lower pole) (OR = 2.193, 95 % CI 1.519-3.166, p < 0.001), number (multifocal) (OR = 2.204, 95 % CI 1.227-2.378, p < 0.001), microcalcification (OR = 1.610, 95 % CI 2.225-4.434, p = 0.002), extrathyroidal extension (OR = 2.204, 95 % CI 1.941-3.843, p < 0.001), maximum diameter of nodule ( ≥ 20 mm) (OR = 3.211, 95 % CI 2.337-4.411, p < 0.001), and C-TIRADS score (OR = 1.356, 95 % CI 1.204-1.527, p < 0.001) were PTC in independent risk factors for CLNM. The C-TIRADS score of PTC combined with the location, number, size, and ultrasound features of the lesion and the patient's sex and age are important in predicting whether they present with CLNM and provide a reference basis for the clinical formulation of a reasonable surgical treatment plan.

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Section: Discussionmentioning

confidence: 99%

Untitled

2023

Horm Metab Res

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Factors of Central Lymph Node Metastasis in Papillary Thyroid Cancer Based on C-TIRADS Analysis

Huang,

Chen,

Zhong

et al. 2023

Horm Metab Res

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To study risk factors for central lymph node metastasis (CLNM) in papillary thyroid cancer (PTC) using the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS). We retrospectively analysed patients who underwent PTC surgery and central lymph node dissection at First People's Hospital of Foshan City. The clinical and ultrasonic data of the patients from 1150 cases were analysed by multivariate regression to evaluate the correlation between grayscale ultrasound (US) features, C-TIRADS score, and the classification of thyroid nodules and CLNM of PTCs. The C-TIRADS score was 3.0±1.0 in the CLNM group, which was higher than that in the non-CLNM group (p<0.001). Sex (male) (OR=1.586, 95% CI 1.232–2.042, p < 0.001), age (≤ 45 years) (OR=1.508, 95% CI 1.184–1.919, p = 0.001), location of nodes (lower pole) (OR=2.193,95% CI 1.519–3.166, p < 0.001), number (multifocal) (OR=2.204, 95% CI 1.227–2.378, p < 0.001), microcalcification (OR=1.610, 95% CI 2.225–4.434, p = 0.002), extrathyroidal extension (OR=2.204, 95% CI 1.941–3.843, p < 0.001), maximum diameter of nodule (≥20 mm) (OR=3.211, 95% CI 2.337–4.411, p < 0.001), and C-TIRADS score (OR=1.356, 95% CI 1.204–1.527, p <0.001) were PTC in independent risk factors for CLNM. The C-TIRADS score of PTC combined with the location, number, size, and ultrasound features of the lesion and the patient's sex and age are important in predicting whether they present with CLNM and provide a reference basis for the clinical formulation of a reasonable surgical treatment plan.

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Clinical significance of extrathyroidal extension to major vessels in papillary thyroid carcinoma

Cited by 2 publications

References 54 publications

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Factors of Central Lymph Node Metastasis in Papillary Thyroid Cancer Based on C-TIRADS Analysis

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