Clinical Significance of Diffuse 18F-FDG Uptake in Residual Thyroid Gland after Unilateral Thyroid Lobectomy

Song, Hee-Sung; Lee, Su Jin; Yoon, Seok-Ho; Lee, Jandee; Soh, Euy Young; An, Young‐Sil; Yoon, Joon-Kee

doi:10.1007/s13139-011-0097-5

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Deltoid muscle and axillary lymph node (ALN) uptake were considered positive if the ipsilateral/contralateral ALN SUVmax ratio was greater than 1.5 times [ 15 ]. The finding of bilateral diffusely increased thyroid uptake with a SUVmax greater than 3.2 was defined as thyroiditis [ 16 , 17 ].…”

Section: Methodsmentioning

confidence: 99%

Evaluation of metabolic changes in FDG PET/CT imaging after mRNA-based COVID-19 vaccination

İŞGÖREN¹,

KÖROĞLU²,

GÖRÜR³

et al. 2022

Turkish Journal of Medical Sciences

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Background/aim It is important to evaluate the vaccine-related metabolic changes on FDG PET/CT to avoid confusing results. We here aimed to assess the frequency and intensity of regional and systemic metabolic PET/CT changes of patients who received the mRNA-based COVID-19 vaccine (BNT162b2-Pfizer/BioNTech) and to analyze possible factors affecting these changes. Materials and methods Among the patients who underwent FDG PET/CT for any indication in our department between July 2021 and December 2021, 129 volunteer patients with a history of COVID-19 vaccination were included in this prospective observational study. Bilateral axillary lymph nodes, ipsilateral deltoid muscle, bone marrow, spleen, thyroid, and liver FDG uptakes were evaluated visually and semiquantitatively for each examination. Results The frequencies of positive axillary lymph nodes after vaccination were 40%, 44.4%, 32.6%, and 44.7% in all, 1st dose, 2nd dose, and heterologous vaccination regimens groups, respectively. Maximum standardized uptake values of spleen, liver, and bone marrow were statistically high in patients with positive axillary lymph nodes than with negative ones (p < 0.05). Positive deltoid muscle uptake and diffusely increased thyroid uptake findings were observed in 10 and 8 patients, respectively. The median time interval between vaccination and imaging was 9.5 days for patients with positive axillary lymph nodes and 17 days for patients with negative nodes. In our study group, only 8 patients had a positive documented history of COVID-19 infection. Conclusion Regional and systemic metabolic changes were occasionally found on FDG PET/CT imaging in patients who received the mRNA-based COVID-19 vaccine. To avoid these timely decreasing changes, we recommend managing the ideal timing of imaging or vaccination and taking a careful history.

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Section: Methodsmentioning

confidence: 99%