Clinical significance of Cyclin D1 by complete quantification detection in mantle cell lymphoma: Positive indicator in prognosis
Yan Yang,
Liling Song,
Ying Yin
et al.
Abstract:Background: The positive expression of Cyclin D1 in immunohistochemical (IHC) staining serves as the cornerstone for diagnosing mantle cell lymphoma (MCL). However, existing literature does not conclusively establish whether the expression ratio and staining intensity significantly influence diagnostic outcomes or patient prognosis. In this retrospective study, the correlation between comprehensive Cyclin D1 quantification and the prognosis of MCL patients was studied.
Methods:The Cyclin D1 protein level was a… Show more
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