“…Breast cancer (BC) is the most pernicious type of cancer and has been ascribed as the second most prime cause of premature mortality among women. Around 1.5 million women (20–59 years) throughout the world and in the Middle East part of the globe are being the victims of this cancer in each year as per global cancer project (GLOBOCAN 2012). , Of note, it has been observed that the female in less developed and in industry-based countries encounters the most common non-dermatologic malignancy, and thus, it has been unveiled as a second vital reason of mortality in the United States and in Europe after lung cancer. , The steady increase in global encumbrance of BC in all ethnicities can be assumed to prevail due to the exogenous factors like lifestyle, reproductive factors, and genetic factors like mutations occurring in breast cancer susceptibility gene 1 (BRCA1) and breast cancer susceptibility gene 2 (BRCA2), manifesting the tumors with more hostile phenotypes and thereby playing a significant role in the etiology of such cancer . The high body mass index (BMI), family history of ovarian or breast cancer, nulliparity or first birth at age greater than 30, late menopause, and postmenopausal hormone therapy can be included as the other most important risk factors of breast cancer .…”