Clinical significance in COPD patients followed in a real practice

Oliveira, Júlio César Mendes de; Aguiar, Isabella de Carvalho; Beloto, Ana Carolina Negrinho de Oliveira; Santos, Israel Reis; Filho, Fernando Sérgio Studart Leitão; Sampaio, Luciana Maria Malosá; Donner, Claudio F.; Oliveira, Luís Vicente Franco de

doi:10.1186/2049-6958-8-43

Cited by 13 publications

(8 citation statements)

References 28 publications

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“…Cough and sputum production are reported by 60-80 % of COPD patients [4,5], yet physicians significantly underappreciate the importance of these symptoms to a patient's well-being [6]. Chronic cough and mucus hypersecretion in COPD are associated with accelerated lung function decline, more frequent exacerbations and earlier mortality [7][8][9].…”

Section: Introductionmentioning

confidence: 97%

Objective Measurement of Cough Frequency During COPD Exacerbation Convalescence

Crooks

Hayman

Innes

et al. 2015

Lung

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Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Cough and sputum production are associated with adverse outcomes in COPD and are common during COPD exacerbation (AE-COPD). This study of objective cough monitoring using the Hull Automated Cough Counter and Leicester Cough Monitor software confirms that this system has the ability to detect a significant decrease in cough frequency during AE-COPD convalescence. The ability to detect clinically meaningful change indicates a potential role in home monitoring of COPD patients.

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Section: Introductionmentioning

confidence: 97%

Objective Measurement of Cough Frequency During COPD Exacerbation Convalescence

Crooks

Hayman

Innes

et al. 2015

Lung

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“…The typical profile of patients with COPD includes multiple comorbidities, ( 4 , 5 ) such as heart disease, ( 6 ) osteoporosis, ( 7 ) type 2 diabetes mellitus, ( 8 ) lung cancer, ( 9 ) and cognitive impairment. ( 10 ) In recent years, the clinical relevance of cognitive impairment has risen, ( 11 ) due to the increase in the prevalence of COPD and the growing interest in the aspects that determine functionality and treatment compliance ( 12 , 13 ) among patients with the disease.…”

Section: Introductionmentioning

confidence: 99%

Cognitive impairment in COPD: a systematic review

et al. 2015

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The objectives of this study were to characterize and clarify the relationships between the various cognitive domains affected in COPD patients and the disease itself, as well as to determine the prevalence of impairment in the various cognitive domains in such patients. To that end, we performed a systematic review using the following databases: PubMed, Scopus, and ScienceDirect. We included articles that provided information on cognitive impairment in COPD patients. The review of the findings of the articles showed a significant relationship between COPD and cognitive impairment. The most widely studied cognitive domains are memory and attention. Verbal memory and learning constitute the second most commonly impaired cognitive domain in patients with COPD. The prevalence of impairment in visuospatial memory and intermediate visual memory is 26.9% and 19.2%, respectively. We found that cognitive impairment is associated with the profile of COPD severity and its comorbidities. The articles reviewed demonstrated that there is considerable impairment of the cognitive domains memory and attention in patients with COPD. Future studies should address impairments in different cognitive domains according to the disease stage in patients with COPD.

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“…Underrepresentation of racial and ethnic minorities is an inherent problem of clinical trials (31). On the other hand, the distribution of spirometric impairment is representative of clinic samples of patients with COPD intermediate between primary care (32) and specialty care samples (33).…”

Section: Original Researchmentioning

confidence: 99%

Domain-Specific Self-Efficacy Is Associated with Measures of Functional Capacity and Quality of Life among Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease

et al. 2014

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The relationship between self-efficacy and health behaviors is well established. However, little is known about the relationship between self-efficacy and health-related indicators among patients with chronic obstructive pulmonary disease (COPD).Objectives: The purpose of this cross-sectional cohort study was to test the hypothesis that the total score and specific subdomain scores of the COPD Self-Efficacy Scale (CSES) are associated with functional capacity and quality of life in a group of patients with moderate to severe COPD.Methods: Relationships were examined in a cross-sectional study of baseline data collected as part of a randomized trial. Self-efficacy was measured using the five domains of the CSES: negative affect, emotional arousal, physical exertion, weather/environment, and behavioral. Measures of quality of life and functional capacity included SF-12: physical and mental composite scores, Chronic Respiratory Questionnaire dyspnea domain, and the 6-minutewalk test. Statistical analyses included Spearman correlation and categorical analyses of self-efficacy ("confident" vs. "not confident") using general linear models adjusting for potential confounders.Measurements and Main Results: There were 325 patients enrolled with a mean age (standard deviation) of 68.5 (9.48) years, 49.5% male, and 91.69% non-Hispanic white. The negative affect, emotional arousal, and physical exertion domains were moderately correlated (range, 0.3-0.7) with the SF-12 mental composite score and Chronic Respiratory Questionnaire dyspnea domain. In models exploring each CSES domain as "confident" versus "not confident" and adjusting for age, sex, race, pack-years, and airflow obstruction severity, there were multiple clinically and statistically significant associations between the negative affect, emotional arousal, and physical exertion domains with functional capacity and quality of life. Conclusions:The aggregated total CSES score was associated with better quality of life and functional capacity. Our analysis of subdomains revealed that the physical exertion, negative affect, and emotional arousal subdomains had the largest associations with functional capacity and quality of life indicators. These findings suggest that interventions to enhance self-efficacy may improve the functional capacity and quality of life of patients with moderate to severe COPD.Keywords: COPD; dyspnea; self-efficacy; quality of life Author Contributions: B.E.J., D.B.C., J.A., K.P.S., and S.B. were involved in the conception, hypothesis generation, and design of the study. B.E.J., K.P.S., M.U., and S.B. were involved in the statistical analysis. D.B.C., R.R., and J.P. were involved in the acquisition of data and interpretation of results.Correspondence and requests for reprints should be addressed to Bradford E. Jackson, Ph.D.,

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Clinical significance in COPD patients followed in a real practice

Cited by 13 publications

References 28 publications

Objective Measurement of Cough Frequency During COPD Exacerbation Convalescence

Objective Measurement of Cough Frequency During COPD Exacerbation Convalescence

Cognitive impairment in COPD: a systematic review

Domain-Specific Self-Efficacy Is Associated with Measures of Functional Capacity and Quality of Life among Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease

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