Clinical significance

Ogles, Benjamin M.; Lunnen, Kirk M.; Bonesteel, K.

doi:10.1016/s0272-7358(99)00058-6

Cited by 194 publications

(52 citation statements)

References 75 publications

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“…An easily interpretable index of clinically significant change was used to operationalize end-state functioning [19]. Consistent with previous research [16], a score on the BDI-II in the minimal range (0–13) was taken to suggest acceptable end-state functioning: acceptable end-state functioning scored ‘1’; unacceptable end-state functioning scored ‘0’.…”

Section: Methodsmentioning

confidence: 99%

Therapist Competence, Comorbidity and Cognitive-Behavioral Therapy for Depression

Kuyken

Tsivrikos

2008

Psychother Psychosom

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Background: Therapist competence has consistently been associated with therapy outcomes, although the nature of this relationship varies considerably across studies. Method: In a naturalistic process-outcome study, 69 clients presenting with depression were treated by 1 of 18 cognitive-behavioral therapists in a ‘real world’ outpatient clinic. Using triangulated measures of therapists’ competence, we hypothesized that greater therapist competence would be associated with improved cognitive-behavioral therapy (CBT) outcomes for clients diagnosed with depression. We hypothesized that the variation in the research to date on therapist competence and CBT for depression outcomes may be due to the moderating effects of complexity of client presentation, in terms of comorbidity. Results: We replicated the previous finding that comorbidity compromises CBT for depression outcomes, but found that greater therapist competence was associated with improved outcomes, regardless of clients’ comorbidity. Conclusions: Therapist competence is associated with improved therapy outcomes, and therapists who are more competent have better patient outcomes regardless of the degree of patient comorbidity.

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Section: Methodsmentioning

confidence: 99%

Therapist Competence, Comorbidity and Cognitive-Behavioral Therapy for Depression

Kuyken

Tsivrikos

2008

Psychother Psychosom

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“…This index is used to determine whether the observed change in measures scores are significant based on reliability of the measures. Also, remission rate was applied to examine clinical significance (31). The remission rate formula was as follows, Remission rate = [baseline-post Therapy]/ post Therapy].…”

Section: Discussionmentioning

confidence: 99%

The Applicability and Efficacy of Transdiagnostic Cognitive Behavior Therapy on Reducing Signs and Symptoms of Borderline Personality Disorder With Co-Occurring Emotional Disorders: A Pilot Study

Mohammadi

Bakhtiari

Arani

et al. 2018

Iran J Psychiatry Behav Sci

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Background: Borderline personality disorder (BPD), which is highlighted by emotional dysregulation and high rates of comorbid emotional disorders, is one of the most challenging clinical conditions for mental health services in different communities. The Unified protocol for the transdiagnostic treatment of emotional disorders (UP) was designed to target common vulnerabilities across emotional co-occurring disorders. Objectives: The aim of the present study was to examine the preliminary efficacy of the UP in treatment of Iranian patients with BPD and comorbid emotional disorders. Methods: By the purposeful sampling method, 6 participants (5 females and 1 male) with borderline personality disorder (BPD) and major depressive disorder (MDD), which met the inclusion criteria, participated in a multiple baseline experimental single case study. Each participant completed the borderline personality inventory (BPI) and difficulties in emotion regulation scale (DERS) during 3 baseline, 8 treatment modules, and 1 follow up assessment session. The unified protocol was carried out for 16 to 20 weekly sessions. Optical analysis and reliable change index (RCI) were used for determination of statistical significance. Remission rate was also applied to measure clinical significance. Results: Results showed that the unified protocol (UP) was effective on reduction of BPD and depressive symptoms as well as increase of emotion regulation skills. Conclusions: The efficacy of UP was statistically and clinically significant in most of the participants. Results from this study provide preliminary evidence for the efficacy of the UP in the treatment of BPD with co-occurring unipolar depressive disorders in Iran, and provide additional support for the transdiagnostic approach in the treatment of emotional disorders.

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“…Although the Jacobson and Truax (1991) method may be the most popular method for assessing clinical significance (Ogles et al, 2001), it is not the only way of conceptualizing the quantification of clinical significance. The Jacobson and Truax method determines whether there is individual change in functioning relative to a comparison group after treatment.…”

Section: Determining Clinical Significancementioning

confidence: 99%

“…Prior to the introduction of clinical significance, this client change was assessed using only traditional analyses and findings that were statistically significant represented an efficacious intervention (Moleiro & Beutler, 2009). There has been, however, a growing recognition among clinical researchers that reliance on traditional inferential statistical analyses to evaluate treatment efficacy is problematic (Kazdin, 1999;Kendall & Sheldrick, 2000;Kraemer et al, 2003;Lunnen & Ogles, 1998) and that statistically significant differences between groups do not necessarily indicate practical, meaningful, or clinically significant differences between groups, nor for individuals within the groups (Ogles, Lunnen, & Bonesteel, 2001). Therefore, when investigators infer the efficacy of certain interventions by referencing statistically significant differences found between two group means following treatment, the ameliorative effect of the intervention is not established and may not be genuine.…”

mentioning

confidence: 99%