“…Regarding histopathology features, perifascicular atrophy, necrosis, inflammation, and neurogenic changes were described in the SSc-overlap group [ 119 ]. Furthermore, in a Hungarian cohort, the genetic features HLA-DRB1 and DQA1 and dysphagia were more common in overlap patients, while some characteristics present at the onset of SSc, such as fever, subcutaneous calcinosis, heart involvement, and claw hand deformity, were correlated with pulmonary arterial hypertension in this group [ 120 , 121 ]. A group of authors also described a seronegative form of scleromyositis, with the absence of SSc-specific or SSc-overlap antibodies, and explored the non-ACR/EULAR features that led to a positive diagnosis of scleromyositis.…”