Clinical screening for GCK-MODY in 2,989 patients from the Brazilian Monogenic Diabetes Study Group (BRASMOD) and the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG)
Renata Peixoto-Barbosa,
Luis Eduardo Calliari,
Felipe Crispim
et al.
Abstract:Objectives: To evaluate the accuracy of routinely available parameters in screening for GCK maturityonset diabetes of the young (MODY), leveraging data from two large cohorts -one of patients with GCK-MODY and the other of patients with type 1 diabetes (T1D). Materials and methods: The study included 2,687 patients with T1D, 202 patients with clinical features of MODY but without associated genetic variants (NoVar), and 100 patients with GCK-MODY (GCK). Area under the receiver-operating characteristic curve (R… Show more
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