Clinical, salivary, and bacterial markers for caries risk assessment in schoolchildren: a 4‐year follow‐up

Sánchez-Pérez, Leonor; Golubov, Jordan; Camacho, María Esther Irigoyen; Moctezuma, Patricia; Acosta-Gío, Enrique

doi:10.1111/j.1365-263x.2008.00941.x

Cited by 23 publications

(24 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Modified Snyder's test has long been reported as a reliable prediction tool for caries increment. [3031] Poor correlation was reported between sugar consumption and caries activity during all time points of measurements throughout the study period. This implies that reduction in caries activity as result of our SOHPP was possibly due to antibacterial topical fluoride varnish[32] and povidone iodine therapy.…”

Section: Discussionmentioning

confidence: 99%

School based oral health promotional intervention: Effect on knowledge, practices and clinical oral health related parameters

Gauba

Bal²,

Jain³

et al. 2013

Contemp Clin Dent

View full text Add to dashboard Cite

Background:No organized school oral health program is existent in India.Aim:The aim of this study is to test the feasibility and efficacy of an economical school oral health promotional intervention with educational and preventive components.Settings and Design:School oral health promotional intervention carried out in one of the randomly selected school and evaluated through short duration prospective model.Materials and Methods:A total of 100 children with an age range of 10-12 years with no previous history of dental intervention were enrolled. Interventions comprised of oral health education (delivered through lecture and demonstrations by an undergraduate dental student) and topical antibacterial therapy (fluoride varnish and povidone iodine). Outcomes consisted of Knowledge and practices (KAP) regarding oral health, clinical oral health related parameters such as plaque index (PI), gingival index (GI) and caries activity as per Modified Snyder's test. These were reported at baseline, 3 weeks and 6 months follow-up examination by a calibrated examiner.Statistical Analysis:McNemar Bowker's test, Student's t-test, Pearson Chi-square tests were used.Results:Highly significant (P < 0.001) improvements in KAP scores, PI scores, GI scores and caries activity were reported at 3 weeks and 6 months follow-up examination.Conclusion:This small economical school oral health program positively influenced oral health related practices and parameters of oral health such as oral cleanliness, gingival health and caries activity.

show abstract

Section: Discussionmentioning

confidence: 99%

School based oral health promotional intervention: Effect on knowledge, practices and clinical oral health related parameters

Gauba

Bal²,

Jain³

et al. 2013

Contemp Clin Dent

View full text Add to dashboard Cite

show abstract

“…Although the positive predictive ability of these models have been shown to be effective for both low and moderate caries risk children, the individual cost and time constraints imposed by a multiple test protocol have been found too restrictive for clinical practice. 10,44,47,61,62 Similar chairside limitations and cost, along with the poor predictive values (both low sensitivity and specificity) for the high risk child, have limited their acceptance by all but the most oral health conscious patient and dental professional. 58,61 Their clinical use in a public oral health setting, where resources are extremely limited, restricts their value and application to predominantly research purposes only at present.…”

Section: Caries Predictionmentioning

confidence: 99%

“…48,49,52,59,60,65,66 Most studies conclude that past caries experience is still the most reliable predictor of future caries experience in children and that a clinician's intuition or 'gut feeling' is often more accurate than current diagnostic technologies. 3,5,7,44,46,47,67,68 Unfortunately, active dental caries presence negates primary disease prevention in a literal MID sense and a clinician's intuition is not easily quantifiable for the statistical validation of this criterion in any prediction model. The challenge to researchers in this field is to identify other accurate and reliable markers for future caries experience that a clinician can use quickly and inexpensively.…”

Section: Caries Predictionmentioning

confidence: 99%

The application of caries risk assessment in minimum intervention dentistry

Hallett

2013

Australian Dental Journal

View full text Add to dashboard Cite

Caries risk assessment forms the cornerstone for the successful application of a minimum intervention dentistry philosophy in the management of dental caries. Patients, particularly those with evidence of active dental caries at baseline, require a caries risk assessment to identify those risk factors that will most likely contribute to the progression of the carious disease process. Once identified, these factors should be eliminated or at least moderated to ensure the disease progression is stabilized before conservative and rehabilitative dental procedures are undertaken. Each individual will present with a slightly different caries risk profile and the principles of a patient centred approach to manage each case should be applied to the individual diagnostic and treatment planning phases of dental care. Current chairside technologies such as caries susceptibility and activity tests can be utilized to provide baseline and follow-up data to assist the dental practitioner in this task. However, clinician intuition or 'gut feeling' has been found to be a better prognostic indicator for future dental caries experience than present caries prediction instruments in most cases. As caries risk data are accumulated and refined at a population, community and individual level, the sensitivity and specificity of the caries risk assessment modelling will improve as will the positive predictive power of the final statistical model algorithm. It is likely that online caries predictive tools will be available for general dental practitioners in the not too distant future to help clinicians formulate accurate caries risk profiles for their patients.

show abstract

“…The rs6441989 is the number 1 in figure 1b, rs2073595 is number 2 and rs11716495 is number 3. Perez et al, 2009]. Those risk factors have been used by some clinicians as risk markers, but notwithstanding, there is not a predictive test that may precisely identify host predisposing conditions [Twetman and Fontana, 2009].…”

Section: Discussionmentioning

confidence: 99%

Lactotransferrin Gene Polymorphism Associated with Caries Experience

et al. 2015

View full text Add to dashboard Cite

Dental caries is a common multifactorial disease, resulting from the interaction of biofilm, cariogenic diet and host response over time. Lactotransferrin (LTF) is a main salivary glycoprotein, which modulates the host immune-inflammatory and antibacterial response. Although a genetic component for caries outcome has been identified, little is known over the genetic aspects underlying its susceptibility. Thus, the aim of this study was to investigate the association between LTF polymorphisms and caries susceptibility. Six hundred seventy seven 12-year-old students were selected: 346 with (DMFT ≥ 1) and 331 without caries experience (DMFT = 0). Also, individuals concentrating higher levels of disease (polarization group, DMFT ≥ 2, n = 253) were tested against those with DMFT ≤ 1 (n = 424). Along with clinical parameters, three representative LTF tag SNPs (rs6441989, rs2073495, rs11716497) were genotyped and the results were evaluated using univariate and multivariate analyses. Allele A for tag SNP rs6441989 was found to be significantly less frequent in the polarization group, conferring a protective effect against caries experience [AA + AG × GG (OR: 0.710, 95% CI: 0.514-0.980, p = 0.045)], and remained significantly associated with caries protection in the presence of gingivitis (p = 0.020) and plaque (p = 0.035). These results might contribute to the understanding of the genetic control of caries susceptibility in humans.

show abstract

Clinical, salivary, and bacterial markers for caries risk assessment in schoolchildren: a 4‐year follow‐up

Abstract: In addition to the initial caries experience, tooth morphology and Snyder test proved to be useful predictors for caries. These three risk markers may be particularly useful in targeting caries prevention efforts in developing countries.

Cited by 23 publications

References 26 publications

School based oral health promotional intervention: Effect on knowledge, practices and clinical oral health related parameters

School based oral health promotional intervention: Effect on knowledge, practices and clinical oral health related parameters

The application of caries risk assessment in minimum intervention dentistry

Lactotransferrin Gene Polymorphism Associated with Caries Experience

Contact Info

Product

Resources

About