2009
DOI: 10.1186/cc8142
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Clinical review: Post-extubation laryngeal edema and extubation failure in critically ill adult patients

Abstract: Laryngeal edema is a frequent complication of intubation. It often presents shortly after extubation as post-extubation stridor and results from damage to the mucosa of the larynx. Mucosal damage is caused by pressure and ischemia resulting in an inflammatory response. Laryngeal edema may compromise the airway necessitating reintubation. Several studies show that a positive cuff leak test combined with the presence of risk factors can identify patients with increased risk for laryngeal edema. Meta-analyses sho… Show more

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Cited by 140 publications
(115 citation statements)
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References 52 publications
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“…It is imperative that anesthesia providers remain extra vigilant in assessing the readiness of the obese patient, as reintubation has clearly been shown to be associated with higher mortality and morbidity. 18 Historically, patients undergoing trial extubation are brought to the operating room. In the presence of a qualified surgeon to perform an emergent tracheostomy, the patient is evaluated for potential extubation.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…It is imperative that anesthesia providers remain extra vigilant in assessing the readiness of the obese patient, as reintubation has clearly been shown to be associated with higher mortality and morbidity. 18 Historically, patients undergoing trial extubation are brought to the operating room. In the presence of a qualified surgeon to perform an emergent tracheostomy, the patient is evaluated for potential extubation.…”
Section: Discussionmentioning
confidence: 99%
“…Interestingly, airway obstruction as a cause for reintubation is associated with a lower mortality rates compared with non-airway causes for reintubation (see figure 3). 18 Figure 3: Incidence of reintubation and mortality 18 SDRP Journal Of Anesthesia & Surgery February 20, 2016 Narjeet Khurmi 3 www. siftdesk.…”
Section: Incidencementioning
confidence: 99%
“…Stridor is treated effectively with an aerosol treatment of racemic epinephrine 2.25% (22.5 mg/mL in 3 mL of normal saline). 29 …”
Section: Extubation Considerationsmentioning
confidence: 99%
“…In the former case, larynx edema is a frequently observed cause of airway obstruction in the ICU and during the postoperative period. On the other hand, in the latter case, the factors contributing to airway obstructions include comorbid diseases, type of disease, and postoperative management (5)(6)(7)(8). This can serve as guidance for clinicians regarding the time for which patients having difficult airways and extubation failure risk in the ICU should be monitored and the duration for which airway exchange catheters should be used, when necessary (9).…”
Section: Determination Of Extubation Failure Riskmentioning
confidence: 99%