Clinical Relevance of RSV and SARS-CoV-2 Coinfections in Infants and Young Children

Rodriguez-Fernandez, Rosa; González-Martínez, Felipe; Perez-Moreno, Jimena; González-Sánchez, María Isabel; Toledo del Castillo, Blanca; Mingueza de la Paz, Irene; Diaz Pozo, Laura; Mejias, Asuncion; Ramilo, Octavio

doi:10.1097/inf.0000000000004080

Cited by 3 publications

(1 citation statement)

References 10 publications

(13 reference statements)

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“…A recent study revealed that co-infection with RSV enhances the severity of SARS-CoV-2 omicron infection in young children. These findings warrant detailed investigations into how RSV and SARS-CoV-2 co-infections impact the disease's outcome in children [48].…”

Section: Influenza and Sars-cov-2 Co-infection: Competition Or Sinist...mentioning

confidence: 90%

SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

Teluguakula,

Chow,

Pandareesh

et al. 2024

Viruses

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The COVID-19 pandemic remains a serious public health problem globally. During winter influenza seasons, more aggressive SARS-CoV-2 infections and fatalities have been documented, indicating that influenza co-infections may significantly impact the disease outcome of COVID-19. Both influenza and SARS-CoV-2 viruses share many similarities in their transmission and their cellular tropism for replication in the human respiratory tract. However, the complex intricacies and multi-faceted dynamics of how the two pathogens interact to ensure their survival in the same lung microenvironment are still unclear. In addition, clinical studies on influenza co-infections in COVID-19 patients do not provide conclusive evidence of how influenza co-infection mechanistically modifies disease outcomes of COVID-19. This review discusses various viral as well as host factors that potentially influence the survival or synergism of these two respiratory pathogens in the infected lung microenvironment.

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Section: Influenza and Sars-cov-2 Co-infection: Competition Or Sinist...mentioning

confidence: 90%

SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

Teluguakula,

Chow,

Pandareesh

et al. 2024

Viruses

View full text Add to dashboard Cite

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The risk of hospitalisation from RSV is not increased by co-infection in children under 24-months-of-age

Ferrari,

Giani,

Scaramuzza

et al. 2024

Eur J Pediatr

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Respiratory Viral Coinfections in Pediatric Patients in the Primary Care Setting: A Multicenter Prospective Study Within the COPEDICAT Network

Andrés,

Perramon-Malavez,

Creus-Costa

et al. 2024

The Journal of Infectious Diseases

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Acute respiratory viral infections pose a significant healthcare burden on the pediatric population globally, but data on the dissemination pattern in the community due to the COVID-19 pandemic are scarce. We conducted a two-year prospective multicenter study in Catalonia (Spain) that examined the prevalence and coinfection dynamics of respiratory viruses among 1276 pediatric patients from different age groups attending primary care. Coinfection analysis demonstrated complex patterns and revealed a coinfection rate of 23.8% for SARS-CoV-2, often in association with rhinovirus or influenza A. This study provides valuable data to understand post-pandemic viral interactions, which is imperative for public health interventions.

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Clinical Relevance of RSV and SARS-CoV-2 Coinfections in Infants and Young Children

Cited by 3 publications

References 10 publications

SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

SARS-CoV-2 and Influenza Co-Infection: Fair Competition or Sinister Combination?

The risk of hospitalisation from RSV is not increased by co-infection in children under 24-months-of-age

Respiratory Viral Coinfections in Pediatric Patients in the Primary Care Setting: A Multicenter Prospective Study Within the COPEDICAT Network

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