Clinical relevance of fatigue levels in cancer patients at a Veterans Administration Medical Center

Hwang, Sun‐Goo; Chang, Victor Tsu-Shih; Cogswell, J.; Kasimis, Basil

doi:10.1002/cncr.10507.abs

Cited by 12 publications

(14 citation statements)

References 10 publications

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“…Consistent with previous research23–24, we hypothesized that a moderate to high level of fatigue would be associated with higher levels of depressed mood, dyspnea, and more functional limitations. Identifying the correlates of fatigue may inform rehabilitation programs to improve the quality of life for NSCLC survivors.…”

Section: Introductionsupporting

confidence: 59%

Fatigue and Functional Impairment in Early-Stage Non-Small Cell Lung Cancer Survivors

Hung

Krebs

Coups

et al. 2011

Journal of Pain and Symptom Management

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Context Fatigue is the most common sequela among non-small cell lung cancer (NSCLC) survivors 1–6 years post-treatment and is associated with functional limitations. Objectives This study examined the prevalence, severity, and correlates of fatigue among early stage NSCLC survivors. Methods Three-hundred fifty individuals diagnosed and surgically treated for Stage IA or IB NSCLC completed a survey that included the Brief Fatigue Inventory (BFI) to assess the prevalence and severity of fatigue. The Self-Reported Karnofsky Performance Scale (SR-KPS) was used as a measure of functional status and was compared with the severity of fatigue though chi-square analyses. Demographic, psychological, and medical correlates of fatigue were examined using logistic regression. Results The prevalence of fatigue was 57%. Forty-one percent (n = 142) of participants had mild fatigue and 16.8% (n = 59) had moderate or severe fatigue (BFI ≥ 4). Among the individuals reporting moderate or severe fatigue, 23.7% (n=14) had significant functional impairment (SR-KPS ≤ 70%) compared to 2.8% (n =8) with mild or no fatigue (χ2 = 58.1, p < 0.001). In the multi-variate analysis, NSCLC survivors with pulmonary disease (OR = 2.28), depressive symptoms (OR = 6.99), and anxiety symptoms (OR = 2.31) were more likely to report experiencing clinically significant fatigue, while those who met physical activity guidelines (OR = 0.29) reported less fatigue. Discussion Fatigue is highly prevalent among NSCLC survivors and associated with more functional impairment. A comprehensive approach to the treatment of fatigue includes the screening and management of anxious and depressive symptoms, and pulmonary disorders such as chronic obstructive pulmonary disease.

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Section: Introductionsupporting

confidence: 59%

Fatigue and Functional Impairment in Early-Stage Non-Small Cell Lung Cancer Survivors

Hung

Krebs

Coups

et al. 2011

Journal of Pain and Symptom Management

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“…[7] Unlike simple tiredness or situational fatigue, it is more debilitating and severe; less likely to be relieved by simple rest; and may lead to withdrawal from meaningful and enjoyable activities and may even lead to discontinuation of treatment. [8] Despite all these, there are only few studies that have quantified the impact of fatigue on overall quality of life (QOL) in cancer patients. The aim of this study is to evaluate the magnitude of fatigue in cancer patients receiving radiotherapy and its relative impact on different QOL domains/subscales.…”

Section: Introductionmentioning

confidence: 99%

Magnitude of fatigue in cancer patients receiving radiotherapy and its short term effect on quality of life

et al. 2010

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“…33 Besides a total QoL score, the scale also provides physical, social/family, emotional, and functional well-being subscale scores (internal consistencies 32 ranging from .63 to .89). 35 The score of 0 corresponded to no fatigue; 1 to 2, mild fatigue; 3 to 6, moderate fatigue; and 7 to 10, severe fatigue. The FACT-G takes approximately 10 minutes to complete.…”

Section: Instrumentsmentioning

confidence: 99%

Psychosocial Characteristics of Cancer Patients Who Choose to Attend an Educational Session on Cancer-Related Fatigue

2008

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Little is known about cancer patients who seek specific educational interventions on cancer-related fatigue (CRF). The objectives of this study were (1) to describe the level of CRF, and emotional distress; social support; coping styles; and quality of life of patients who chose to attend a 1-hour educational session on CRF and (2) to examine the relationship between the selected demographic, psychosocial, and treatment-related variables and CRF. A questionnaire-based survey of 41 cancer patients who volunteered after a 1-hour education session on CRF at the Tom Baker Cancer Centre was conducted. The sample consisted mostly of married white women who lived in an urban environment. The average age was 56 years, and participants had an average of 14 years of education; 78% of the sample reported moderate to severe fatigue, 27% had significant levels of emotional distress, and 63% had a problematic coping style. Higher fatigue was associated with emotional distress, poorer quality of life, hopelessness, and reduced social support. To conclude, patients who self-refer to an educational session on CRF present a wide range of emotional difficulties and problematic coping styles. Therefore, educational sessions with patients with CRF should emphasize coping with emotional distress and building a support system.

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Clinical relevance of fatigue levels in cancer patients at a Veterans Administration Medical Center

Cited by 12 publications

References 10 publications

Fatigue and Functional Impairment in Early-Stage Non-Small Cell Lung Cancer Survivors

Fatigue and Functional Impairment in Early-Stage Non-Small Cell Lung Cancer Survivors

Magnitude of fatigue in cancer patients receiving radiotherapy and its short term effect on quality of life

Psychosocial Characteristics of Cancer Patients Who Choose to Attend an Educational Session on Cancer-Related Fatigue

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