Clinical Relevance of Drug Interactions in HIV-Infected Patients Receiving Antiretroviral Therapy

Amariles, Pedro; Alzate, Newar Giraldo; Faus, María José

doi:10.5772/19408

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“…Our patient experienced profuse night sweats followed by generalized jerky movements of the body similar to a tonic-clonic seizure. We were unable to explain this reaction as she did not have other risks for seizures and paracetamol interaction with other medications including the antiretroviral drugs she was taking was unlikely [7,8]. She tolerated other medications very well.…”

Section: Discussionmentioning

confidence: 99%

Reported Case of Paracetamol and Non-Steroidal Anti- Inflammatory Drug (NSAID)-Induced Seizures in a Patient with HIV Infection

Enwere¹,

Eze²

2014

Trop. J. Pharm Res

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Commonly available analgesics, such as paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs), are used widely with few or no adverse events by most individuals. However, some adverse events have been observed following the use of these drugs. This paper reports a case of paracetamol and NSAID-induced seizures in a patient with the human immunodeficiency virus infection/acquired immune deficiency syndrome (HIV/AIDS). These seizures occurred at different times, first with paracetamol and then diclofenac (a NSAID). She was concurrently on anti-retroviral drugs and

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Section: Discussionmentioning

confidence: 99%