Clinical relevance of Chinese syndrome factors and thromboelastography levels in patients with phlegm-heat and fu-organ excess syndrome

Wu, Shuang; Chen, Pei; Zou, Yihuai; Jiang, Lan; Geng, Hualei; Yan, Ruyu; Wang, Shan; Zhu, Li

doi:10.1016/j.jtcms.2019.07.002

Cited by 1 publication

(1 citation statement)

References 22 publications

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“…Patients with Phlegm-Dampness syndrome are considered to be susceptible to multiple metabolic diseases [ 116 ]. This could be attributed to the fact that Phlegm tends to accumulate in different body parts, which might give rise to various diseases such as acne [ 58 ], AIDS [ 59 ], asthma [ 60 ], autism [ 62 ], obesity [ 73 ], type 2 diabetes mellitus [ 67 , 70 , 116 ], coronary artery disease [ 66 ], coronary heart disease [ 65 ], metabolic syndrome [ 73 ], NAFLD [ 72 ], hypertension [ 70 ], hyperlipidemia [ 69 ], bronchiectasis [ 63 ], stroke [ 74 ], AD [ 57 ], scrofula [ 75 ], and epilepsy [ 117 ] ( Table 1 ). Table 1 lists the diseases associated with leaky gut and Phlegm syndromes, which are considerably similar.…”

Section: The Relation Among Phlegm Syndrome Leaky Gut and Inflammentioning

confidence: 99%

The Interrelationships between Intestinal Permeability and Phlegm Syndrome and Therapeutic Potential of Some Medicinal Herbs

Park

Choi²,

Kang

et al. 2021

Biomolecules

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The gastrointestinal (GI) tract has an intriguing and critical role beyond digestion in both modern and complementary and alternative medicine (CAM), as demonstrated by its link with the immune system. In this review, we attempted to explore the interrelationships between increased GI permeability and phlegm, an important pathological factor in CAM, syndrome, and therapeutic herbs for two disorders. The leaky gut and phlegm syndromes look considerably similar with respect to related symptoms, diseases, and suitable herbal treatment agents, including phytochemicals even though limitations to compare exist. Phlegm may be spread throughout the body along with other pathogens via the disruption of the GI barrier to cause several diseases sharing some parts of symptoms, diseases, and mechanisms with leaky gut syndrome. Both syndromes are related to inflammation and gut microbiota compositions. Well-designed future research should be conducted to verify the interrelationships for evidence based integrative medicine to contribute to the promotion of public health. In addition, systems biology approaches should be adopted to explore the complex synergistic effects of herbal medicine and phytochemicals on conditions associated with phlegm and leaky gut syndromes.

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