1987
DOI: 10.1016/s0140-6736(87)91106-8
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Clinical Relevance of a Serological Cross-Reaction Between Escherichia Coli 0157 and Brucella Abortus

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Cited by 21 publications
(23 citation statements)
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“…Detection of serum agglutinating antibodies was used with some success by Notenboom et al 17 In our study, 17 (60.7%) of 28 cases had titres of agglutinating antibody 2 160, whereas this was true of only nine (26.4 %) of 34 control patients ; this simple, rapid and economical test may be a useful adjunct to laboratory diagnosis.…”
Section: Discussionmentioning
confidence: 53%
“…Detection of serum agglutinating antibodies was used with some success by Notenboom et al 17 In our study, 17 (60.7%) of 28 cases had titres of agglutinating antibody 2 160, whereas this was true of only nine (26.4 %) of 34 control patients ; this simple, rapid and economical test may be a useful adjunct to laboratory diagnosis.…”
Section: Discussionmentioning
confidence: 53%
“…Patients with yersiniosis or brucellosis have been shown to raise antibodies which react with the LPS of E. coli 0157 [this study, 13] [10]. Where serology alone provides evidence of infection these cross-reactions should be taken into consideration.…”
Section: Elisamentioning
confidence: 99%
“…This similarity in LPS composition has been used to explain antigenic cross-reactions between Y. enterocolitica 09 and B. abortus, and E. coli 0157 and B. abortus, detected with hyperimmune rabbit sera [10][11][12]. Sera from patients with yersiniosis have been shown to contain antibodies which react with B. abortus [4] and, similarly, patients with brucellosis raise antibodies which crossreact with E. coli 0157 [13]. Studies from this laboratory have shown that patients with HUS, caused by E. coli 0157, raise antibodies that react with the LPS of B. abortus [5,6].…”
Section: Introductionmentioning
confidence: 99%
“…The presence of antibodies in sera from patients with HUS against the lipopolysaccharide (LPS) of E. coli O157 was reported initially by Notenboom et al (23). Subsequent studies designed to characterize the immune responses of patients infected with E. coli O157 have reported the presence of immunoglobulin M (IgM) (8), IgG (16), and both IgM and IgG (1) antibodies to O157 LPS in patients with HUS.…”
mentioning
confidence: 96%