Clinical Reasoning: Unusual headaches

Osorio, Maria Joana; Bhatia, Poonam; Zuccoli, Giulio; Holder, Deborah

doi:10.1212/wnl.0b013e3182343286

Cited by 2 publications

(2 citation statements)

References 7 publications

(5 reference statements)

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“…These patients typically present with refractory seizures and/or episodes of headache. A literature review conducted by Jallo, et al in 2005 found that sporadic MA has a mean age of 18.6 years, and is mostly in the temporal and frontal lobes [ 2 , 5 - 6 ]. The operative course is typically unremarkable for recurrence, except in cases of incomplete resection.…”

Section: Discussionmentioning

confidence: 99%

“…Meningioangiomatosis (MA) is a benign, hamartomatous lesion typically described as an intracortical plaque-like proliferation of meningothelial or fibroblast-like cells around vessels [ 1 - 2 ]. First reported in 1915 [ 3 - 4 ], MA occurs in up to 3% of tumor patients presenting with intractable epilepsy [ 5 ]. MA may occur sporadically, or in association with neurofibromatosis type II (NF2) in up to 50% of patients [ 2 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

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Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases

Anand

Garling

Poulik

et al. 2017

Cureus

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Meningioangiomatosis (MA) is a rare benign, hamartomatous lesion within the leptomeninges and cerebral cortex. Three percent of intractable epileptic patients with tumor develop MA. It may be accompanied with neurofibromatosis type II, or it may occur sporadically.Three patients, age range of 2-16 years old, presented with episodes of seizure. The patients demonstrated no family history or stigmata of neurofibromatosis type II. Electroencephalogram (EEG) was unremarkable for epileptiform activity. Magnetic resonance imaging (MRI) revealed enhancing lesions within the frontal gyrus, the anterior cingulate gyrus, and the parietal lobe. Incomplete resection led to recurrence in one patient, and later, intraoperative ultrasound was used to achieve total resection in another patient. Each patient was seizure free on follow-up, and managed with anti-epileptic medication.Resection is the only curative treatment in 85% of MA cases. Complete resection is necessary for symptomatic treatment in cases of MA, as recurrence has been documented in this lesion. Intraoperative ultrasound is an effective imaging modality to ensure gross total resection of MA.

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Section: Discussionmentioning

confidence: 99%