Clinical Reasoning: A young man with acute encephalopathy, loss of vision, and upper motor neuron signs

Elkhider, Hisham; Mesraoua, Boulenouar; Ibrahim, Wanis H; Vattoth, Surjith; Abbas, Salma O.; Deleu, Dirk

doi:10.1212/wnl.0000000000002407

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…By searching the Medline databases, 18 reports of 19 patients met the criteria of posterior reversible encephalopathy syndrome with spinal cord involvement. 2,5 -21 Including the present 2 patients, this study comprised a total of 21 cases for descriptive analysis. Among the 21 cases, 8 are children (<18-year-old).…”

Section: Resultsmentioning

confidence: 99%

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Posterior Reversible Encephalopathy Syndrome With Spinal Cord Involvement in Children

et al. 2016

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We characterized a cohort of patients with posterior reversible encephalopathy syndrome with spinal cord involvement. We encountered 2 children and identified an additional 19 patients from the internet databases. Of the 21 patients analyzed, 8 were children. The mean peak systolic blood pressure in adults was significantly higher than in children (221.8 ± 14.3 vs 191.4 ± 31.3 mm Hg; P < .01). Regardless of age, the most common clinical symptom was headache (90%) and the least common clinical symptom was seizures (28%). Atypical neuroimaging was more common in children (63%) than in adults (8%). Abnormal cerebrospinal fluid results were frequently found in children (83%). All children recovered uneventfully, but 3 adults had sequelae. A broader clinicoradiologic spectrum makes the diagnosis of children more complex than in adults. Awareness of the atypical features with a meticulous management of hypertension is imperative to avoid unnecessary invasive workups and to achieve an uneventful recovery.

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Section: Resultsmentioning

confidence: 99%

“…All children obtained uneventful recovery of clinicoradiologic abnormalities after promptly normalizing blood pressure, but 3 male adults had sequelae including weakness of legs, exaggerated deep tendon reflexes in the lower limbs with bilaterally positive Babinski reflex, and impaired vision. 2,17,20…”

Section: Resultsmentioning

confidence: 99%

Posterior Reversible Encephalopathy Syndrome With Spinal Cord Involvement in Children

et al. 2016

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“…PRES-SCI presentation is slightly different with the classical PRES (c-PRES) [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. Patients with PRES-SCI 2-23 seems to be younger than those within c-PRES with male predominance.…”

Section: Discussionmentioning

confidence: 99%