Clinical prognostic scoring system to aid decision-making in gastro-oesophageal cancer

Abstract

This model accurately estimated the probability of death within 12 and 24 months. This may aid the MDT decision-making process.

Carcinoembryonic antigen and cytokeratin 20 in peritoneal cells of cancer patients: are we aware of what we are detecting by mRNA examination?

“…Nevertheless, prognosis for PCR-positive patients was shown to be significantly worse than for PCR-negative patients, and this was in accordance with the recent data of Crumley et al (2006) and Deans et al (2007), who linked inflammation symptoms with adverse prognosis in patients with gastric cancer. However, there are simpler and cheaper methods than qRT-PCR to assess inflammatory parameters.…”

Association of C-Reactive Protein Levels and Long-Term Survival after Neoadjuvant Therapy and Esophagectomy for Esophageal Cancer

“…Deans et al included the CRP (≤5 versus >5 mg/l) in a risk score model for gastroesophageal cancer. 26 Patients with a raised CRP level over 5 mg/L had a 2.6 times higher probability of death from their disease.…”

The influence of systemic inflammation, dietary intake and stage of disease on rate of weight loss in patients with gastro-oesophageal cancer

“…It is also important to consider that the relative importance of these components may change during the course of an individual patient's illness, highlighting the need for periodic re-assessment and flexibility in terms of nutritional and therapeutic intervention. In addition, accelerated weight loss may provide one of the mechanisms by which systemic inflammation acts to reduce survival duration in a variety of different types of cancer (Falconer et al, 1995;Scott et al, 2002;Lamb et al, 2006;Deans et al, 2007).…”