Clinical Prognosis of Superior Versus Basal Segment Stage I Non-Small Cell Lung Cancer

Prognostic significance of basal versus superior segment in patients with completely resected lung adenocarcinoma in the lower lobe

“…Although Handa et al . reported that superior segment tumors had a higher incidence of mediastinal lymph node metastasis than basal segment tumors in patients with clinical stage I (clinical N0) lower lobe NSCLC, the difference was not significant . Tomizawa et al .…”

“…10 Although Handa et al reported that superior segment tumors had a higher incidence of mediastinal lymph node metastasis than basal segment tumors in patients with clinical stage I (clinical N0) lower lobe NSCLC, the difference was not significant. 11 Tomizawa et al also reported that no significant difference existed in subcarinal or superior mediastinal lymph node metastasis between superior and basal segment tumors in the right lower lobe. 12 Our study showed that basal segment tumors had a significantly higher possibility of developing N2 lymph node metastasis than superior segment tumors in patients 3.574 2.109-6.058 < 0.001 †The hazard ratio (HR) associated with age is the increase in hazard associated with a one-year increase in age.…”

“…The prognostic factors of lung cancer in a specific lobe, for example, the lower or upper lobe, have not been well demonstrated. Several reports have examined the prognostic value of tumor location (basal vs. superior segment) in lower lobes . In a study of 139 patients with pN2 NSCLC, Watanabe et al .…”

“…Anatomically, the lower lobe can be divided into two parts, the superior and basal segments. The prognostic factors of tumors located in a specific lobe of the lung, such as the lower lobe, have not been well demonstrated in the literature . Watanabe et al .…”

“…The prognostic factors of tumors located in a specific lobe of the lung, such as the lower lobe, have not been well demonstrated in the literature. [10][11][12] Watanabe et al reported that superior and basal segment lung cancers in the lower lobe have different lymph node metastatic pathways to the mediastinum. 10 In the present study, we investigated the relationships between tumor location (basal vs. superior segment) and clinicopathological variables, and the prognostic significance of tumor location in patients with completely resected lung adenocarcinoma in the lower lobe.…”