Clinical profiles of patients with myocardial infarction without obstructive coronary artery disease in Iran

Abstract

Introduction: Myocardial infarction without obstructive coronary artery disease (MINOCA) accounts for 5-15% of acute myocardial infarction (MI) cases. Objectives: The purpose of this study is to determine the prevalence of diabetes, hypertension, hyperlipidemia, smoking, and family history of cardiovascular diseases (CVDs) and their association with gender in patients with MINOCA. Patients and Methods: Around 1772 patients entered this cross-sectional study. Prevalence of diabetes, hypertension and hyperlipidemia was significantly higher in women compared to men (P<0.001). Smoking was more common in men than women (P<0.001). Results: Women with MINOCA are more likely to have hypertension, hyperlipidemia and diabetes than men with MINOCA, whereas men are more likely to be smokers. Conclusion: Effective blood pressure control, correction of lipid profile and proper glycemic control can prevent MINOCA and its associated morbidities and mortality, especially in women.

Cell or cell derivative-laden hydrogels for myocardial infarction therapy: from the perspective of cell types

“…2 Among CVD-related deaths, myocardial infarction (MI) and associated heart failure are the most common causes. 3 MI is triggered by the sudden narrowing or blockage of coronary arteries, which leads to a prolonged reduction or cessation of blood supply to the heart. 4 Myocardial cells undergo necrotic apoptosis during ischemia due to the lack of oxygen or nutrients.…”