Clinical profile of young Indian women presenting with acute coronary syndrome

Nagamalesh, U.M.; Abhinay, T; Naidu, K.C. Karthik; Ambujam, N; Hegde, Anupama; Prakash, Varsha

doi:10.4103/jcpc.jcpc_48_17

Cited by 7 publications

(12 citation statements)

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“…25 in Karnataka which also supports the fact that single vessel disease is the most common type of coronary artery involved in which 49% had Left anterior descending involvement and 21% had left circumflex involvement and only 6% had right coronary artery involvement. 4 To create confusion igavarapu et al did a study in the young Indian population were it showed LAD artery was frequently involved artery but on contradicting the above statement left coronary artery is the least involved in this study. 5 To get rid of confusion on looking in to the Tamil nadu literature which was given by Narayanasamy et al, and showed significant proximal LAD stenosis was seen in 37% of patients, 27% had mid LAD lesion and 38% had distal LAD lesion.…”

Section: Coronary Involvement Of Cad In the Youngmentioning

confidence: 65%

“…Among multiple symptoms, UN Nagamalesh et al, states that 95% of patients presented with typical chest pain. 4 But another study shows young CAD patients denied any chest pain. 20 On comparing diabetic and, non-diabetic Atypical chest pain is more common in diabetic population.…”

Section: Clinical Profile Of Young Cadmentioning

confidence: 99%

“…Another study published by Nagamalesh et al, also says that Anterior wall MI is the most common MI in young adults. 4 A survey conducted among young Indians around 2017 and showed that 47% of patients had anterior wall MI, 37% of patients had inferior wall MI, 7.5%, and 5% had inferior with posterior and inferior with RV MI. 10% of patients were presented with Non-ST-T segment MI.…”

Section: Clinical Profile Of Young Cadmentioning

confidence: 99%

“…3 The reason for the difference in the clinical presentation of CAD in younger age group is because of its varying pathophysiology and nature of coronary involvement and hence the management strategies also differs. 4 More aggressive intervention is required in many of them for improving the morbidity and mortality. 5 At present, the arbitrary age 45 years and below is taken as cutoff age to say young in most of the studies.…”

Section: Introductionmentioning

confidence: 99%

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Profile of acute coronary syndrome in young diabetics: a review

Narayanan

Hanifah

2020

Int J Adv Med

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The clinical presentation and angiographic findings of coronary artery disease (CAD) varies from diabetic and non-diabetic patients and varies with the age of presentation. Coronary artery disease in patients below the age of 45 is a special subset. The objective of this study is to compare the clinical and angiographic profile in patients with the acute coronary syndrome (ACS) with diabetes mellitus (DM) and without DM below the age of 45 years. Clinical Presentation of coronary artery disease in young patients with various risk factors differs, which plays an important role in management strategies. This was conducted through internet search on PubMed and ProQuest database from 2000 to until 2019. Key words used for searching are acute coronary syndrome, young diabetics, and clinical, angiographic profile. An important exclusion criterion is studies which included type one diabetic patients. Totally 35 papers were reviewed. Pattern of involvement of coronary arteries as assessed by the coronary angiographic study is found to be different in younger CAD patients. Atypical clinical presentation and distinct angiographic finding are common in diabetics below the age of 45. In most of the studies single vessel disease (SVD) is the most common angiographic finding in young CAD and non-diabetics. While the diabetics showed the more diffuse pattern of double vessel disease (DVD).

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Section: Coronary Involvement Of Cad In the Youngmentioning

confidence: 65%

Section: Clinical Profile Of Young Cadmentioning

confidence: 99%

Section: Clinical Profile Of Young Cadmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Profile of acute coronary syndrome in young diabetics: a review

Narayanan

Hanifah

2020

Int J Adv Med

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“…The percentage of dyslipidemia in our study was comparable to Bhandari et al, 68% and Nagamalesh et al, 69.8%. 6,11 Low HDL with or without high TG is very common among Indians and genetic factors may be involved. Conversely, people with low TG-high HDL levels have a low risk of CAD, but this profile is uncommon among Asian Indians.…”

Section: Dyslipidaemiamentioning

confidence: 99%

A cross sectional study of acute myocardial infarction in young individuals below 40 years and associated risk factors in Mandya institute of medical sciences, Mandya, Karnataka

2021

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Background: Acute coronary syndrome (ACS) is a potentially life‑threatening condition which is more common in elderly people, and young are relatively protected. Its incidence in young Indians is about 12-16%. Currently, the protective effect on young from coronary artery disease (CAD) is taken away by several risk factors. The aim of this study is to determine the conventional and new emerging risk factors like hyperhomocysteinemia and lipoprotein a (Lp [a]) which are suggested to play an important role in myocardial infarction (MI). Methods: This study was a hospital‑based retrospective cross‑sectional analytical study involving 61 patients aged ≤40years presented with signs and symptoms of ACS confirmed by ECG changes and cardiac enzyme levels admitted in the cardiac ICU from April 2019 to March 2020.Results: Although ACS is a less common entity in young adults aged ≤40 years, smoking was the most common cause of the MI (75%) in young adults. Homocysteine and Lp (a) should be measured in young MI patients. Smoking cessation and prevention of diabetes and hypertension (HTN) should be encouraged.Conclusions: Smoking was the most common cause of the MI (75%) in young adults and is the major modifiable risk factor for MI in very young patients which needs strict prevention. Young patients with CAD were mainly males. There is a need for early detection of a risk factor to prevent the progression of ACS,

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Risk factors, lab parameters, angiographic characteristics and outcomes of coronary artery disease in young South Asian patients: a systematic review

Agrawal,

Lamichhane,

Eghbali

et al. 2023

J Int Med Res

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This systematic review provides a qualitative summary of the risk factors, angiographic characteristics, treatment, and complications of young South Asians with coronary artery disease (CAD). PubMed, Embase, and Google Scholar were searched to identify research articles published between 1 January 2010 and 13 November 2022. Studies in patients aged 18 to 45 years that were conducted in South Asian countries, were published in the English language, and included information on patients’ clinical profiles and at least two risk factors for young CAD were included in the review. Smoking, dyslipidemia, high body mass index, increased high-sensitivity C-reactive protein, and hyperhomocysteinemia were observed in high proportions in young patients with CAD. Single-vessel disease was more common than multi-vessel disease in young CAD. The complications of CAD such as arrhythmias, cardiogenic shock, and heart failure were also commonly observed in young patients. Large-scale health promotion activities that curb modifiable risk factors such as smoking, obesity, and a sedentary lifestyle should be conducted in South Asian countries.

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Clinical profile of young Indian women presenting with acute coronary syndrome

Cited by 7 publications

References 0 publications

Profile of acute coronary syndrome in young diabetics: a review

Profile of acute coronary syndrome in young diabetics: a review

A cross sectional study of acute myocardial infarction in young individuals below 40 years and associated risk factors in Mandya institute of medical sciences, Mandya, Karnataka

Risk factors, lab parameters, angiographic characteristics and outcomes of coronary artery disease in young South Asian patients: a systematic review

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