Clinical Profile of Type 1 Diabetes Mellitus in Saudi Children: a Hospital Based Study

Rafique, Muhammad; Ishaq, Fouzia; Masood, Muhammad Khalid; Alqahtani, Youssef A.; Assiri, Walaa Ibrahim Ahmed; Assiri, Manal Ahmed Ali; Qureshi, Muhammad Atif; Zia, Shumaila

doi:10.21649/akemu.v22i4.1458

Cited by 3 publications

(6 citation statements)

References 18 publications

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“…The commonest symptom being polyuria 33 (78.6%) followed by polydipsia 27 (64.3%), weight loss 23 (54.8%) and polyphagia 13 (30.9%) which is comparable to other studies. 11,20 In present study, family history of diabetes in first degree relative was 9 (21.4%) which is similar to the studies from India (26.4%) and Bangladesh (22.2%). 12,21 In contrast, studies from Saudi Arab (34%) and Libya (48%) revealed high prevalence of family history of diabetes.…”

Section: Discussionsupporting

confidence: 88%

“…10 In contrast, studies from Saudi Arabia (6.8±3.2 years) and Bangladesh (9±3.9 years) reported younger age of onset. 11,12 Minimum age at the time of diagnosis in present study was 17 months. Mean duration of symptoms before diagnosis was more than two weeks which is comparable to a study from Europe.…”

Section: Discussionmentioning

confidence: 71%

“…16,17 But some of the studies, 17% Egypt, 46.7% Arab countries and 22% Saudi Arab had less prevalence of DKA at presentation. 11,18,19 The older age at diagnosis and high incidence of DKA in present region is probably due to delay in hospital visit and lack of awareness of diabetic symptoms in parents. The commonest symptom being polyuria 33 (78.6%) followed by polydipsia 27 (64.3%), weight loss 23 (54.8%) and polyphagia 13 (30.9%) which is comparable to other studies.…”

Section: Discussionmentioning

confidence: 95%

“…12,21 In contrast, studies from Saudi Arab (34%) and Libya (48%) revealed high prevalence of family history of diabetes. 11,22 Majority of the patients were from rural areas 26 (61.9%). In addition, a study from Finland also showed similar findings.…”

Section: Discussionmentioning

confidence: 99%

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Clinical profile of type 1 diabetes mellitus among children in eastern part of Nepal

Muktan

Tamang²,

Singh

2019

Int J Contemp Pediatr

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Background: The objective of this study is to determine the clinical profile of Type 1 diabetes mellitus (T1DM) among children.Methods: Descriptive cross sectional study was conducted at B.P. Koirala institute of Health Sciences (BPKIHS), Dharan, Nepal, the eastern part of Nepal. A total of 42 diabetic children of less than 20 years old diagnosed with T1DM were included in the study. Data were collected via semi-structured interviews and medical records of patients attending diabetic clinic at the time of follow up.Results: The mean age at diagnosis of disease was 11.1±4.9 years. Polyuria 33 (78.6%) was found to be the commonest symptom followed by polydipsia 27 (64.3%), weight loss 23 (54.8%) and polyphagia 13 (30.9%). The mean duration of symptoms before diagnosis was 14.3±9.7 days. DKA was present in 25 (59.5%) children at the time of diagnosis. Mean Glycosylated hemoglobin (HbA1c) value was 10.6±2.7. Obesity was observed in 9 (21.4%) children. Nine (21.4%) children had family history of diabetes. In most of the cases, primary caregiver was mother, among them only 24 (57.2%) had formal education. Almost half of the caregivers were using FRIO, an insulin cooling case, for insulin storage.Conclusions: Polyuria was the most common presenting symptom followed by polydipsia, weight loss and polyphagia. Moreover, most of the children had landed up in diabetic keto-acidosis (DKA) at the time of diagnosis. Therefore, community awareness programs should be emphasized among parents and primary health care workers especially in rural areas regarding T1DM for early recognition and prompt treatment.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 71%

Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

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Clinical profile of type 1 diabetes mellitus among children in eastern part of Nepal

Muktan

Tamang²,

Singh

2019

Int J Contemp Pediatr

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“…Classic symptoms like polyuria, polydipsia, weight loss were the main presenting symptoms in our study population, similar observation was reported in other studies also. 12,13,14 In this study Diabetic ketoacidosis at initial presentation was noticed in more than half of the subjects. The reported frequency of DKA as the primary presentation varies from 15 -67% in type I diabetes in children.…”

Section: Discussionmentioning

confidence: 60%

Clinico-Laboratory Characteristics and Immediate Outcome in Children With Diabetes Mellitus

Padma¹,

Krishnan²

2019

jemds

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BACKGROUND Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia resulting from an absolute or relative deficiency of insulin. The burden of childhood diabetes is rising all over the world. METHODS This is a descriptive study conducted at a tertiary care hospital. Eighty-five children with diabetes mellitus admitted during the study period were included. Clinical details, laboratory parameters were collected from the medical records and the data was analysed using statistical tests. RESULTS Eighty-five children less than 12 years were included in this study. Female: male ratio was 1.43:1. Age wise distribution was 0-5 years (28.24%), 5-10 years (40%), 10-12 years (31.76%). Majority of them were from lower socioeconomic class (71.76%). Family history of diabetes mellitus was present in forty-one children. Majority of them presented with osmotic symptoms like polyuria (82.35%), polydipsia (80%). Forty-six children presented with diabetic ketoacidosis. Type 1 diabetes was diagnosed in 88.24% of the subjects. There were two children with Type 2 diabetes mellitus. The mean RBS at presentation was 470.42±125.02 and the mean HbA1c was 11.05 ± 1.98. There was no statistically significant difference in the duration of onset of symptoms to diagnosis between the ketotic and non ketotic group. The BMI was in the range 10 to 25, with mean value 15.09 ± 3.39. There was no mortality among the subjects. CONCLUSIONS Type 1 diabetes is still the predominant form of diabetes among children. Osmotic symptoms like polyuria, polydipsia are the most common presenting symptoms. Younger children are more prone to have diabetic ketoacidosis. Awareness of diabetes care is essential for the successful management of the disease.

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Clinical and biochemical profile of childhood–adolescent-onset type 1 diabetes and adult-onset type 1 diabetes among Asian Indians

et al. 2023

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Clinical Profile of Type 1 Diabetes Mellitus in Saudi Children: a Hospital Based Study

Cited by 3 publications

References 18 publications

Clinical profile of type 1 diabetes mellitus among children in eastern part of Nepal

Clinical profile of type 1 diabetes mellitus among children in eastern part of Nepal

Clinico-Laboratory Characteristics and Immediate Outcome in Children With Diabetes Mellitus

Clinical and biochemical profile of childhood–adolescent-onset type 1 diabetes and adult-onset type 1 diabetes among Asian Indians

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