Clinical Profile of Sickle Cell Anaemia in Adolescent and Adult Patients in Central India

Abstract

BACKGROUNDSickle cell anaemia is a commonly encountered inherited haematological disorder in Central India. Despite the unicity of the genetic mutation that is responsible, clinical presentation of the sickle cell haemoglobinopathy was found to be different according to regions and patients. Aims and Objectives-To study the clinical profile of sickle cell anaemia with particular reference to vaso-occlusive crisis and to estimate the quantity of foetal haemoglobin (HbF) with High Performance Liquid Chromatography (HPLC).