Clinical Profile of Pediatric Neurological Disorders

Mohamed, Inaam N.; Elseed, Maha A.; Hamed, Ahlam A.

doi:10.1177/2329048x15623548

Cited by 17 publications

(15 citation statements)

References 19 publications

(17 reference statements)

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“…[1][2][3][4][6][7][8][9] On the contrary, the prevalence rate is similar to the reported prevalence in Sudan. 10 However, a higher prevalence may be obtained from community-based studies as some patients, especially those with myopathies, may be confined to their homes. 5 The addition of disorders whose etiology is from the central nervous system such as cerebral palsy in some of these studies could have also contributed to the higher prevalence.…”

Section: Discussionmentioning

confidence: 99%

“…The male preponderance is similar to the higher number of males reported in the United Kingdom population of children with NMD. 10 This may be due to the fact that myopathies such as Duchenne muscular dystrophy is inherited in X-linked recessive mode making it mainly expressed in males. However, the male predominance was seen across all the categories of NMDs.…”

Section: Discussionmentioning

confidence: 99%

“…Mohamed et al reported NMDs as contributing 3.2% of pediatric neurology cases seen at a pediatric outpatient clinic in Sudan. 10 In a community survey done more than 30 years ago on neurological disorders among Nigerian Africans, peripheral nerve disorders were the group of NMDs with the highest prevalence ratio with a ratio of 268:100,000 population. 11 Epilepsy and headache had significantly higher prevalence ratio.…”

Section: Introductionmentioning

confidence: 99%

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Pediatric Neuromuscular Disorders in Ile-Ife, Nigeria: Pattern and the Challenges with Management

Olorunmoteni

Kareem

Ayogu

2020

Journal of Pediatric Neurology

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To describe the presentation pattern and challenges with the management of pediatric neuromuscular disorders (NMDs) in Ile-Ife, Nigeria through retrospective review of their clinical records. We recruited 24 children aged 14 days to 15 years with a male preponderance (male-to-female ratio = 2.4:1). Late presentation was a prominent feature which was highest among children with myopathies with a mean duration of symptoms of 46.5 ± 33.4 months before presentation. Peripheral neuropathy was the most common type of NMDs (63.0%). Among these, injection nerve palsy from the use of wrong site for intramuscular injections was the most common (60.0%). Nonavailability of electrophysiologic and genetic testing as well as appropriate medications was the major challenges. Acquired NMDs are common in our setting. There is a need to improve preventive measures of acquired NMDs and early diagnosis of the inherited types.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pediatric Neuromuscular Disorders in Ile-Ife, Nigeria: Pattern and the Challenges with Management

Olorunmoteni

Kareem

Ayogu

2020

Journal of Pediatric Neurology

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“…3 It is also known that insufficient or lack of stimulation of the auditory cortex during the allimportant periods of plasticity invariably affects adversely the function of hearing, language and vision development. 4 It has also been found that there is sex predilection among children with neurological disorders with the male sex predominating. 5 Epilepsy and seizure disorders are the commonest neurological disorders seen and managed in most clinics.…”

Section: Introductionmentioning

confidence: 99%

Hearing among children with neurological disorders

Uju

Nneka

2020

Int J Res Med Sci

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Background: Neurologic disorders are not rare in our environment but studies determining the hearing of these children are almost non- existent. This study therefore is to determine the prevalence of hearing loss in these children and also determine the care seeking attitude of the parents/guardians concerning the hearing.Methods: A hospital based descriptive study of all children attending the children neurologic clinic of university of Port Harcourt teaching hospital. A semi structured questionnaire was administered to parents / guardians who gave their consent for their children to be recruited into the study. Hearing loss in the children was taken as reported by the parents/guardians. Data collected were then entered into Microsoft Excel and then exported to the IBM Statistical Package for Social Sciences (SPSS) version 20 for statistical analysis.Results: The study comprised 49 children; 29 males and 20 females. Age range was from 8months to 18years. Age group 1-5 years comprised the majority of the study population. Commonest neurological disorder seen was childhood epilepsy n=27, 55.1%. Prevalence of hearing loss was 26.5%. Children with childhood epilepsy had 15.4% having hearing loss while children with cerebral palsy, autistic spectrum disorder and microcephaly had 50% hearing loss recorded. Maternal illness during pregnancy was significantly related to the hearing loss with a p value = 0.045 and presence of neonatal illness with p value =0.009. Only 7.7% was formally treated while 92.3% had no form of treatment whatsoever.Conclusions: Childhood epilepsy was the commonest type of neurologic disorder seen while highest point prevalence for hearing loss was in cerebral palsy. Majority of parents/caregivers did not seek medical care concerning the hearing loss neither were there any form of treatment given to the children.

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“…We have tried to pay attention to lesser addressed issues of uncommon findings, dysmorphic features, rare diseases [9,10] or chronic neurological problems. [11,12] marked with limited therapy, poor outcome, desperate situation, superimposed with high economic, physical and mental burden to family, along with its detrimental effect on micro economy of the country.…”

mentioning

confidence: 99%

Health and Disease Profile of Children in Remote Rural Pockets of Himachal Pradesh, With a Look-Out for Uncommon and Rare Diseases- A Collage of Health Camp Based Cross Sectional Study

Hajela¹

2019

jemds

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BACKGROUND Health camp organization is an established mode of health care delivery to unreached rural population deprived of specialist care. Himachal Pradesh is a hilly area with difficult to travel geographical terrain. Our institute organized multispecialty health camps in remote rural pockets of Himachal Pradesh including paediatrician's services. METHODS Health status and disease profile of children who attended these camps were entered in a predesigned proforma. Haemoglobin estimation was done on the spot. Data of 472 children attending 20 such camps were analysed. RESULTS 7.84 % children came for paediatric consultation from 6019 patients who attended these camps. Maximum number of patients were in age group of 6-12 years. 25.6 % children had a weight for age < 3 rd percentile and an almost a similar number of 25.4 % had height less than <3 rd percentile for age, suggestive of malnutrition and short stature respectively. 78.8 % children had anaemia of varying degree. 36.7 % children were brought with long duration of illness lasting for more than one year and another 5.51% had problems since birth. The most common presenting complaint was pain abdomen with gastrointestinal tract, the most commonly involved system. Children suffering with uncommon & rare diseases, various Syndromes and CNS diseases were also found hidden in these rural pockets without any diagnostic or therapeutic help. CONCLUSIONS The study highlights a delayed health care seeking behaviour in rural children and parents. Anaemia is still a big problem in spite of many health programs in place for decades. Protein energy malnutrition is prevalent, and it is manifesting in the form of stunting in almost 25% of attended child population. A paediatrician-oriented specialist care for early diagnosis and management of these children is the need of hour. A lookout for uncommon diseases is required to address this issue in India to keep pace with global health care approach.

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Clinical Profile of Pediatric Neurological Disorders

Cited by 17 publications

References 19 publications

Pediatric Neuromuscular Disorders in Ile-Ife, Nigeria: Pattern and the Challenges with Management

Pediatric Neuromuscular Disorders in Ile-Ife, Nigeria: Pattern and the Challenges with Management

Hearing among children with neurological disorders

Health and Disease Profile of Children in Remote Rural Pockets of Himachal Pradesh, With a Look-Out for Uncommon and Rare Diseases- A Collage of Health Camp Based Cross Sectional Study

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