Clinical profile of keratoconus patients in Sudan

Abdu, Mustafa; Binnawi, Kamal Hashim; Elmadina, Abd Elaziz Mohamed; Hassan, Ramadan

doi:10.4103/1858-540x.184235

Cited by 13 publications

(29 citation statements)

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“…According to the results, 15.2%, 56.4%, and 28.4% of the patients had mild, moderate, and severe KCN, respectively. The frequency of moderate and severe KCN in our study was similar to its frequency in Asian populations but higher than in other ethnic populations, especially European populations,4, 5, 6, 18, 22, 35, 37, 48 which confirms that patients with a more advanced disease seek management in Asian countries.…”

Section: Discussionsupporting

confidence: 85%

“…Considering the marked relationship between KCN and ethnicity, 7 clinical/topographic indices of KCN in each population are unique to the population, and the clinical characteristics in different ethnic populations cannot be replaced or adapted to each other. Considering the importance of the knowledge of demographic profile and clinical/topographic indices of KCN, different studies have evaluated these parameters in different ethnic populations 18, 19, 20, 21, 22, 23, 24. Some epidemiological studies have also been carried out in this field in Iran,8, 25, 26, 27 but the aim of these studies was mainly to determine the prevalence of the KCN.…”

Section: Introductionmentioning

confidence: 99%

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Demographic profile, clinical, and topographic characteristics of keratoconus patients attending at a tertiary eye center

Rafati

Hashemi

Nabovati

et al. 2019

Journal of Current Ophthalmology

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PurposeTo evaluate the demographic profile, clinical, and topographic characteristics of keratoconus (KCN) patients attending at a subspecialty eye hospital in Tehran, Iran.MethodsIn this cross-sectional study, all patients who attended Noor Eye Hospital between March 2011 and March 2017 and had a diagnosis of KCN were identified, and the required number of patients was randomly selected. The following data were extracted from patient's records: age, sex, visual acuity, refraction, keratometry, pachymetry, and treatment procedures. The data of KCN laterality, severity, morphology, and cone location were also extracted by analyzing the corneal imaging maps.ResultsThe records of 1080 eyes of 540 patients were evaluated. The mean age of the participants was 31.04 ± 8.54 years (range, 13–63 years), and 69.3% of the patients were male. The highest and lowest frequency of KCN was seen in the age group 20–30 years and above 50 years, respectively. Bilateral KCN was detected in 93.3% [95% confidence interval (CI): 91.68–94.75] of the subjects. 43.7% (95%CI: 32.88–54.48), 55.6% (95%CI: 44.73–66.38), and 0.8% (95%CI: 0.75–0.78) of the cases had nipple, oval, and globus cones, respectively. The cone was central in 52.1% (95%CI: 41.10–63.11), paracentral in 43.6% (95%CI: 36.13–51.04), and peripheral in 4.3% (95%CI: 00.76–7.86) of the cases. The frequency percentage of KCN according to severity was 15.2% (95%CI: 13.09–17.46), 56.4% (95%CI: 53.37–59.37), and 28.4% (95%CI: 25.75–31.21) for mild, moderate, and severe KCN, respectively. Among different parameters, only cone location had a significant association with age as the frequency of paracentral and peripheral cones increased with ageing (P = 0.002).ConclusionsThe mean age of KCN patients in our study was higher than similar studies in other Asian countries. KCN was bilateral in most cases with an oval morphology and central cone location. Most of the patients had moderate to severe KCN.

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Section: Discussionsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Demographic profile, clinical, and topographic characteristics of keratoconus patients attending at a tertiary eye center

Rafati

Hashemi

Nabovati

et al. 2019

Journal of Current Ophthalmology

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“…In the current study, the majority of cases were compound myopic astigmatism (69.7%) that is found in all grades and age groups of the disease and significantly found that compound myopic astigmatism with the rule was more likely to be associated with Severe keratoconus (21.9%) ,in moderate grade (21.6%) and in mild grade (13.4%) where (P value =0.002) , followed by simple myopic astigmatism (25.4%), mixed astigmatism (3.2%) which is not present in severe keratoconus and those patient with age >40 years, it was more frequent in mild keratoconus probably due to the corneal curvature was close to emmetropia, then the simple myopia (1.7%). This finding is comparable with Aníbal Cruz-Becerril et al results which concluded that compound myopic astigmatism was the commonest refractive error among patients with keratoconus, being present in (87.5%) of eyes, simple myopic astigmatism (5.5%) , mixed astigmatism in (4.7%) and myopia was present in (0.8%) [35].…”

Section: Discussionsupporting

confidence: 89%

“…Our study showed that the mean age of patients with keratoconus was (24.9 ± 7.9), which is comparable with the results of other studies as those done in Asia by Saini G et al [33], they found the mean age of patients was (21.3±6.96), study done by Pearson AR, Soneji B, Sarvananthan N, et al [34] on white patients, showed that the mean age was (26.5 ± 8.5 years) and a study done in Mexican by Aníbal Cruz-Becerril et al [35] reported that the mean age was (28.14±10.30).…”

Section: Discussionsupporting

confidence: 88%

Prevalence of Refractive Errors in Patients with Keratoconus among Sample of Iraqi Population

Kf¹

2017

OAJO

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Background: Kerato-conus is a progressive disease of the cornea with deformed keratometry readings, characterize by progressive thinning of corneal apex and corneal ectasia. Keratoconus can affect each layer of the cornea. Keratoconus present in patients with teenage groups and early twenties with complaints of deterioration of vision and frequent change of glasses due to alteration in refractive state of them who develops different types of astigmatism, commonly myopic one. Aim of Study: The prevalence of refractive errors in patients with keratoconus to explain their clinical characteristics. Patients & Methods: This is a retrospective cross sectional research study, in which the clinical data in recorded files were reviewed, (343) eyes of (180) patients with keratoconus, among them (110) were females and (70) were males consulting Al-Najaf refractive surgery center and Al-Hakeem general hospital for correction of their refractive errors during the period between May, 2016 through February, 2017. Results: The commonest refractive error that present in all grades and age groups of the disease is compound myopic astigmatism (69.7%) followed by simple myopic astigmatism (25.4%), mixed astigmatism (3.2%) then the simple myopia (1.7%). Conclusion: The prevalence of keratoconus was higher among patients between (10 to 30) years old. Females were the dominant gender but no significant difference detected in grades of keratoconus and refractive error between genders.

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“…The finding of more males using contact lenses in the study suggests that males are more affected by keratoconus than females, which is similar to findings in many studies. [7][8][9]38 However, there is currently no consensus as other research revealed higher prevalence in females 32,35 or no significant difference between genders. 39 The current study could highlight contexts where males are more culturally, academically and economically empowered than females (38), which enables them to more easily access and afford healthcare services.…”

Section: Discussionmentioning

confidence: 99%

<p>Visual Acuity and Refractive Error Improvement in Keratoconic Patients: A Low-Income Context Management Perspective</p>

Yego

Moodley

2020

OPTO

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Introduction: Visual acuity (VA) and refractive error (RE) remain important parameters in the management of keratoconic (KC) patients. Despite rapid amelioration in capacity of diagnostic equipment, these remain inaccessible to the majority of practitioners in lowincome countries. Notwithstanding limitations, practitioners are expected to utilize existing resources to satisfactorily manage their increasing numbers of keratoconic patients. Purpose: To determine the changes in visual acuity and refractive errors with diagnostic and management options available in low-income contexts. Methods: A descriptive, retrospective chart analysis of medical records dating back 5 years was employed in this study. Records of patients prescribed with corneal rigid gas permeable (RGP) and scleral lenses were analyzed. Data on age, gender, stage of keratoconus, pre-, and post-visual acuities and refractive errors, mode of correction and lens parameters were evaluated. Results: A total of 124 medical records were analyzed. Males comprised 58.9% and females 41.1% of the total sample, with a mean age 20.86 ± 9.50 years. The mean unaided VA in logMAR notation was 1.0±0.19, while corrected VA was 0.18±0.17. There was a significant improvement (p=0.001) in VA with corneal RGP contact lenses (mean 0.19±0.17) as compared to unaided VA (mean 1.29±0.20). Scleral lens VA also improved from a median of 1.06 to −0.01 logMAR; p=0.001. The mean RE before RGP contact lens fitting was −9.43 ±2.37 diopters (D) which improved to −0.41±0.78D. RE reduced significantly (p=0.001) after fitting with both corneal RGP lenses (from a mean of −9.80±4.46D to −0.45±0.80D) and scleral lenses (from a median of −8.00D to −0.02D). Conclusion: Significantly improved visual acuity and refractive error status were achieved with all KC patients. Despite the diagnostic equipment and contact lenses design limitations, practitioners in low-income contexts can fit the relatively more affordable corneal RGP lenses to positively impact the daily living experiences of their KC patients.

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Clinical profile of keratoconus patients in Sudan

Cited by 13 publications

References 0 publications

Demographic profile, clinical, and topographic characteristics of keratoconus patients attending at a tertiary eye center

Demographic profile, clinical, and topographic characteristics of keratoconus patients attending at a tertiary eye center

Prevalence of Refractive Errors in Patients with Keratoconus among Sample of Iraqi Population

<p>Visual Acuity and Refractive Error Improvement in Keratoconic Patients: A Low-Income Context Management Perspective</p>

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