Clinical Profile of Diabetic Foot Ulcers of Patients Attending Surgical Opd in Rural Medical College

Abstract

OBJECTIVETo study the clinical profile of dibetic foot ulcers of patients attending surgical OPD in rural medical college. MATERIAL AND METHODSClinical profile of 40 patients of diabetic foot ulcers was studied. All the patients were subjected to complete haemogram, fasting and PP blood sugar, LFT, KFT, lipid profile, urine R/E, pus c/s, colour doppler of lower limb and x-ray foot. RESULTSMajority of patients with diabetic foot ulcers were of age group 41-70, male, diabetes mellitus of duration more than 6 years, had intermittent claudication and single ulcer. KEYWORDSDiabetes, Foot, Ulcer. HOW TO CITE THIS ARTICLE: INTRODUCTIONDiabetes mellitus is a metabolic disorder associated with longterm vascular and neurological complications. Diabetic foot is one of the common complications of diabetes affecting the quality of life of patients; 20% of total diabetic population have foot problems. Foot ulcers occur in 5%-10% of all diabetic patients and upto 3% will have lower limb amputations during their lifetime. The overall risk for amputation is increased in diabetics 15 times beyond that for non-diabetic people. 1 Diabetic foot is the end point of neuropathy and PVD and amputation is the end point of diabetic foot. In India the reported incidence is 2%-29%. 2,3,4 Foot ulcers are cutaneous erosions characterised by a loss of epithelium that extends into or through the dermis to deeper tissues. Minor trauma often footwear related has been reported as the most frequent event leading to lower extremity ulcer and subsequent amputations.Despite many major advances in health care delivery to patients with diabetes, foot problems contiue to extract a heavy toll on the quality of life of diabetic patients. The high morbidity and mortality, loss of working hours, expenditure associated with diabetic foot problems necessitate the need for a prompt and proper approach to foot ulcer management.

Revolutionizing Cancer Treatment: The Promising Horizon of Zein Nanosystems

“…33 By encapsulating these agents within zein nanoparticles, researchers aim to achieve targeted delivery to cancer cells, thereby increasing the drug's therapeutic efficiency while minimizing side effects. 38,43 This targeted approach is crucial in oncology, as it allows for the direct attack on cancer cells while sparing healthy tissues, leading to better patient outcomes. 36,37,44−46 Additionally, zein nanosystems are being explored in the realm of gene therapy.…”