Clinical Profile of COVID-19 in Children and Research Progress on Angiotensin-converting Enzyme 2: A Mini-review

Gao, Qian; Liu, Jing; Mu, Zhilong; Yan, Xianpeng; Shah, Jay; Jiao, Fuyong

doi:10.31729/jnma.5436

Cited by 2 publications

(2 citation statements)

References 24 publications

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“…[22][23][24] Unlike children who are less affected and have mild symptoms with a shorter course of the disease, the elderly are more impacted by COVID-19. 25,26 There is a need for specific interventions to meet the requirements of elders for assisted living environments to maintain good health, and survive the disaster like coronavirus pandemic. 27 The majority of medical students and interns, 95% out of 200 participants in the present study, knew about the precautionary measure applied during aerosol-generating procedures (AGPs).…”

Section: Resultsmentioning

confidence: 99%

Knowledge and perceptions towards COVID-19 among final year undergraduate medical students and interns in Province 2, Nepal

Shah

Panjiyar

Sah

et al. 2020

J Patan Acad Health Sci

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Introduction: Corona Virus Disease-19, the COVID-19, has become a pandemic of public health concern, more so for developing countries like Nepal with an inadequate and vulnerable health system. Among all the seven provinces of the country, Province-2 seems to be at higher risk due to population density and open porous border with neighboring India. This survey was conducted among the undergraduate medical students of medical colleges in Province-2, Nepal to evaluate their knowledge and perception regarding the prevention and spread of the virus. Method: A descriptive cross-sectional study was conducted in September 2020 among final-year undergraduate medical students and interns from Janaki Medical College in Janakpur and National Medical College in Birgunj of Province-2, Nepal. A structured 30-item questionnaire containing demographics (5 items), knowledge (15 items), and perception (10 items) regarding COVID-19 was used for an online survey via email. Ethical approval was taken. Descriptive analysis was performed. Result: A total of 200 out of 250 respondents (>95%) had an adequate level of knowledge on etiology, symptoms, hand hygiene, severity, vulnerability, precautionary measures, and treatment guidelines of COVID-19. More than 80% were ready to work in the hospital during the pandemic with support from their family and nearly half of them (49%) perceived that the preparedness and supplies were sufficient in their institutions. Conclusion: The survey revealed that the majority of the final-year medical students and interns in Province-2 Nepal had adequate knowledge and perception regarding COVID-19.

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Section: Resultsmentioning

confidence: 99%

Knowledge and perceptions towards COVID-19 among final year undergraduate medical students and interns in Province 2, Nepal

Shah

Panjiyar

Sah

et al. 2020

J Patan Acad Health Sci

Self Cite

View full text Add to dashboard Cite

show abstract

“…1,2 Coronavirus disease 2019 (COVID- 19) is increasingly reported in children. 3,4 There is a concern for the hyperinflammatory state of COVID-19 and KD in multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS). [5][6][7][8] Kawasaki-like disease with cardiac involvement and macrophage activation syndrome (MAS) has been reported from COVID-19 affected areas.…”

Section: Introductionmentioning

confidence: 99%

Kawasaki Disease- Management Strategies Given Symptoms Overlap to COVID-19: A Review

Wang

Zhang

et al. 2021

J Nepal Med Assoc

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Kawasaki disease is an acute, self-limiting vasculitis in children. Early treatment is necessary to prevent cardiovascular complications. The acute phase of Kawasaki disease may present with hemodynamic instability. An association between viral respiratory infections and Kawasaki disease has been reported. Studies have shown that Kawasaki and Kawasaki-like disease may be associated with and have symptoms overlapping COVID-19. Children with COVID-19 may present as Kawasaki-like disease with pediatric inflammatory multisystem syndrome, or macrophage activation syndrome. Clinicians need to be aware of the early diagnosis and management of Kawasaki disease to prevent the development of coronary artery aneurysms. The symptoms overlap of multisystem inflammatory disease seen in COVID-19 adds to the difficulties in timely diagnosis and treatment. Children with Kawasaki disease require regular follow-up plans for coronary artery aneurysms. This adds to the difficulties during the changed environment of COVID-19 for control and prevention. Missed diagnosis and early treatment of Kawasaki disease with immunoglobulin and aspirin results in the development of coronary artery aneurysm in up to 25% of cases, with grave consequences. Here, we briefly review the management of typical and atypical Kawasaki disease which has symptoms overlapping with the multisystem inflammatory disease as seen in COVID-19.

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Clinical Profile of COVID-19 in Children and Research Progress on Angiotensin-converting Enzyme 2: A Mini-review

Cited by 2 publications

References 24 publications

Knowledge and perceptions towards COVID-19 among final year undergraduate medical students and interns in Province 2, Nepal

Knowledge and perceptions towards COVID-19 among final year undergraduate medical students and interns in Province 2, Nepal

Kawasaki Disease- Management Strategies Given Symptoms Overlap to COVID-19: A Review

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