Clinical profile and treatment outcomes of patients with rheumatoid arthritis at a tertiary care hospital of Pakistan

Khaliq, Taqdees; Khan, Atif Ahmed; Malik, Iftikhar Ahmed

doi:10.5455/jpma.289952

Cited by 13 publications

(19 citation statements)

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“…In our study, the incidence was 51.0%. Khaliq et al ( 29 ) speculated that such deformities are rarely seen in Western countries secondary to the prompt diagnosis and treatment of the disease, contrary to the previously published studies [ 3 , 5 , 8 , 31 ]. We have difficulty in explaining the relatively lower incidences of erosive disease in Western countries.…”

Section: Discussionmentioning

confidence: 91%

“…It has been accepted that almost 40% of the patients show extra-articular manifestations of the disease [ 27 , 29 , 30 ]. In this study, we did not calculate an overall rate for extra-articular manifestations.…”

Section: Discussionmentioning

confidence: 99%

“…The erosive disease seen in younger patients is also a significant risk factor for refractoriness to the biological agents [ 31 ]. Previous studies reported the incidence of erosive arthritis in RA populations was ranged up to 86% [ 3 , 5 , 7 , 8 , 27 , 29 , 31 ]. In our study, the incidence was 51.0%.…”

Section: Discussionmentioning

confidence: 99%

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Demographic and Clinical Characteristics of Patients with Sustained and Switching Treatments Using Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs: A Multicenter, Observational Cross-Sectional Study for Rheumatoid Arthritis

et al. 2021

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Introduction: Rheumatoid arthritis is a chronic inflammatory disease with different disease activity grades. Several registries have been designed to determine the appropriate regimens of disease-modifying antirheumatic drugs to obtain sustained clinical remission. We examined epidemiological and clinical characteristics of rheumatoid arthritis patients using a clinical registry database (BioSTaR) and analyzed the differences in patients with sustained and switched therapies. Methods: A multicenter, observational crosssectional study for rheumatoid arthritis was

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

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Demographic and Clinical Characteristics of Patients with Sustained and Switching Treatments Using Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs: A Multicenter, Observational Cross-Sectional Study for Rheumatoid Arthritis

et al. 2021

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“…3 Thus, RA is considered as a disease with a significant impact on all domains of quality of life. 4 Aside from disease prevalence, many pieces of literature also describe the comorbidity condition of patients with rheumatoid arthritis. Hypertension, depression, metabolic disorders like diabetes mellitus and dyslipidemia were frequently observed comorbidities along with altered blood pressure and glucose levels and high cardiovascular risk score as modifiable risk factors.…”

mentioning

confidence: 99%

“…There was a high prevalence of joint deformities. 4 Despite this earlier lack of attention, several studies in the literature assessing knowledge of RA and its physical aspects among Pakistan population. However, no studies have been conducted specifically on women to determine the influence of different sociodemographic and clinical factors affecting the quality of life of Pakistani women with RA.…”

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confidence: 99%

Predictors of quality of life of Pakistani women with rheumatoid arthritis: a cross-sectional study

Sharma

Eapi

Muqtadir

et al. 2021

Int J Community Med Public Health

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Background: Rheumatoid arthritis (RA) is characterized as a chronic inflammatory disease indicated by stiffness, pain, inflammation, and impaired mobility. This results in joint impairment, poor workability, productivity, and afterward, it curtails the quality and expectancy of life of an individual. The aim of this research is to assess the quality of life of Pakistan women with RA and assess various factors affecting it.Methods: It was a cross-sectional study conducted in the Orthopedics department of the Indus Hospital and Health Network, Karachi Pakistan, where we assessed quality of life in sample of women with RA. A consecutive sampling technique was used to enrol women with rheumatoid arthritis who were seen in the Orthopedics outpatient clinic during the study period (February to May 2021).Results: Of the 134 women with RA, 72.39% of women were unemployed, 54.48% of women had family monthly income of 16000 PKR or more and 44.03% of women reported at least one comorbidity other than RA. According to linear regression analyses, women having RA with severe disease activity tended to have tended to have low physical functioning, vitality, emotional wellbeing, social functioning, pain and general health as compared to patients with remission, low disease and moderate disease activity. Absence of family support in disease management can impact vitality and emotional wellbeing with decrease in scores of -85.20 and -120.66 respectively.Conclusions: Guidelines need to developed and implemented for assessing psychological domains of these patients for assessment of quality of life. This will help in maintaining and improving QoL of women with RA.

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An Updated Review on Rheumatoid Arthritis (RA): Epidemiology, Pathophysiology, Diagnosis, and the Current Approaches for Its Treatment

Ashiq,

Mobashar

et al. 2023

Sudan JMS

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Rheumatoid arthritis (RA) is a systemic self-inflicted inflammatory disease that primarily affects middle-aged women. Globally, 1% of people live with RA. This review aims to provide updated information on the different aspects of RA, including its epidemiology, pathophysiology, diagnosis, treatment, and management. A web-based literature search was conducted through various databases, including PubMed, Google Scholar, and Science Direct, to identify the most relevant studies. Epidemiological studies have suggested that the prevalence and occurrence of RA have remained inconsistent across geographical areas in different periods. Many factors such as age, gender, inheritances, and environmental exposure can contribute to the severity of the disease. The acute form of RA usually presents with pain, and if left untreated, it can result in joint deformities and influence a patient’s quality of life (QoL). RA diagnosis is usually based on the manifestation of pain with inflammation. Currently, many therapeutic strategies are available for the cure of RA. The management of daily routine activities is required with treatment to curtail the damage, avoid future deformities, and ultimately minimize the aching trouble of the patient.

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Clinical profile and treatment outcomes of patients with rheumatoid arthritis at a tertiary care hospital of Pakistan

Cited by 13 publications

References 0 publications

Demographic and Clinical Characteristics of Patients with Sustained and Switching Treatments Using Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs: A Multicenter, Observational Cross-Sectional Study for Rheumatoid Arthritis

Demographic and Clinical Characteristics of Patients with Sustained and Switching Treatments Using Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs: A Multicenter, Observational Cross-Sectional Study for Rheumatoid Arthritis

Predictors of quality of life of Pakistani women with rheumatoid arthritis: a cross-sectional study

An Updated Review on Rheumatoid Arthritis (RA): Epidemiology, Pathophysiology, Diagnosis, and the Current Approaches for Its Treatment

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