Clinical profile and predictors of outcome in congenital duodenal obstruction

Chandrasekaran, Sankkarabarathi; Asokaraju, Anirudhan

doi:10.18203/2349-2902.isj20173396

Cited by 6 publications

(12 citation statements)

References 5 publications

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“…Several congenital disorders are known to be closely related to congenital duodenal obstruction, namely Down syndrome (trisomy 21), congenital heart defects, renal anomalies, esophageal atresia, tracheoesophageal fistula, anorectal malformations, lumbar hernia, and biliary anomalies. 2,17…”

Section: Accompanying Congenital Abnormalitiesmentioning

confidence: 99%

“…Several types of surgery can be performed for congenital duodenal obstruction, such as gastrojejunostomy, duodenojejunostomy, and duodenoduodenostomy. 2,18 This study aims to identify the above factors and their influence on mortality prognosis in patients with congenital duodenal obstruction.…”

Section: Description Of the Conceptual Frameworkmentioning

confidence: 99%

“…1 Although the mortality cases of congenital duodenal obstruction are only about 5%, this abnormality remains a burden in pediatric surgery. 2 Congenital duodenal obstruction is divided into total and partial obstruction types. Total obstruction includes duodenal atresia which may be accompanied with annular pancreas.…”

mentioning

confidence: 99%

“…These types of surgery are thought to also affect the prognosis of mortality in patients with congenital duodenal obstruction. 2 This study aims to identify prognostic factors for mortality in patients with congenital duodenal obstruction in Dr. Moewardi Hospital.…”

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confidence: 99%

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Prognostic factors for mortality in patients with congenital duodenal obstruction at DR. Moewardi Hospital Surakarta

Estiarla

Agustriani²

2021

Precision Medical Sciences

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Background: Congenital duodenal obstruction is the most common congenital abnormalities in newborn. Almost 50% of all cases of congential abnormalities is duodenal obstruction. Several conditions of congenital obstruction can worsen a patient's prognosis, such as prematurity, low birth weight (LBW), other congenital abnormalities, type of obstruction, and the type of surgery performed. Objective: To identify prognostic factors for mortality in patients with congenital duodenal obstruction in Dr. Moewardi Hospital Surakarta. Methods: This study was a retrospective descriptive study with cross-sectional approach. Data of congenital duodenal obstruction patients were taken from inpatient medical records from January 2019 to December 2020 at Dr. Moewardi Hospital, Surakarta. Diagnosis, gestational age, birth weight, type of obstruction, other congenital abnormalities, and surgical procedure performed were also recorded. The data were then processed using SPSS 25.0, and one-way Fisher's Exact test was performed. Results: From 20 samples of patients with congenital duodenal obstruction, most of them were born at term pregnancy were 13 patients (65%). There were 11 (55%) babies who died. Based on the type of obstruction, total obstruction type were 12 (60%) patients with mortality rate 81.8%. 13 patients (65%) had comorbid congenital abnormalities. The most commonly performed surgical procedure was duodenojejunostomy (45%). Fisher's Exact test also showed statistically significant data (P = 0.04). Conclusion: There were 20 samples with congenital duodenal obstruction. The total obstruction type had the highest mortality rate. Other variables such as gestational age, birth weight, and other congenital abnormalities did not significantly influence mortality in this study.

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Section: Accompanying Congenital Abnormalitiesmentioning

confidence: 99%

Section: Description Of the Conceptual Frameworkmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Prognostic factors for mortality in patients with congenital duodenal obstruction at DR. Moewardi Hospital Surakarta

Estiarla

Agustriani²

2021

Precision Medical Sciences

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“…Congenital duodenal obstruction (CDO) referred to a broad term including a variety of anomalies such as duodenal atresia, duodenal stenosis, annular pancreas, duodenal membrane, and preduodenal portal vein, 1 is the most common anomalies in newborns and infants. 2 In the pediatric population, the incidence is estimated to be in 20,000 to 40,000 births, with incomplete obstructive lesions including duodenal webs accounting for only 2% of these defects.…”

Section: Introductionmentioning

confidence: 99%

The relationship between sepsis and timing achievement of peristaltic function in congenital duodenal obstruction

Rahmaania

Sastiono

2019

NRJS

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Introduction.Intestinal obstruction has been shown to induce bacterial translocation and in turn, would be associated with an increased risk of sepsis. Such a condition would be affecting the achievement of peristaltic and ultimately increased morbidity and mortality. In addition, nosocomial infections that threaten neonates cause sepsis also will affect the achievement of a peristaltic. Thus, the aim of this study was to investigate the relationship between sepsis with timing achievement of peristaltic postoperatively. Method. This is a cross-sectional study with data obtained from medical records of patients with duodenal obstruction without congenital abnormalities (gastroschisis, omphalocele, and another intestinal atresia) that underwent operations in RSCM during the period of January 2010 to July 2016. Subjects were grouped into sepsis and without sepsis. The association between sepsis and timing achievement of peristaltic, and confounding variables (gestational age, birth weight, congenital abnormalities, conditions of hypoxia and electrolyte imbalance) were analyzed. Data analyzed using univariate, bivariate (Mann Whitney, Chi-Square or Fischer) and multivariate (linear regression) with the significance of <0.05. Results. The study enrolled a total of 31 subjects. Period to achieve peristaltic (median value) was 12.5 days in subjects with sepsis and 5 days in those without sepsis. Bivariate analysis between timing achievement of peristaltic were sepsis (p <0.0001), gestational age (p = 0.004) and hypoxic conditions (p = 0.02). The multivariate analysis showed an association between sepsis and timing achievement of peristaltic (p = 0.011, R 2 = 35.8%). Conclusion. In this study, sepsis was a major factor affecting the achievement of a peristaltic. The time difference to achieved peristaltic between sepsis and without sepsis was significance. Thus, it is necessary to control and prevent sepsis preoperatively and postoperatively that in turn, reducing morbidity and mortality.

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