Clinical profile and outcome of pediatrics tetanus: the experience of a tertiary hospital in Ethiopia

Tadele, Henok

doi:10.4314/ejhs.v27i5.14

Cited by 12 publications

(13 citation statements)

References 13 publications

(17 reference statements)

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“…The relative incidence of tetanus is higher in neonatal age group due to improper sterilization but tetanus is still seen in older age group in under developed countries with inadequate vaccination coverage. In our study the children were in post neonatal age and we found that mean age of presentation was 7.5±3.4 years consistent with 8 years in a study from Ethiopia and a study by Alhaji et al showing mean age of 6.9±3.87 years 2,7. Our study revealed that brunt of burden is born by age group of 5-10 years with 45.5% cases followed by <5 years (30.3%).…”

Section: Discussionsupporting

confidence: 88%

“…Regarding the lack of awareness and practices about the booster doses a study from Nigeria teaching hospital showed that none of the patients received booster dose after their first birthday 9. Quite contradictory to this fact of lack of booster doses of tetanus toxoid a study from a developing country by Tadele showed booster vaccination in 29% of the patients 2…”

Section: Discussionmentioning

confidence: 95%

“…Tetanus is caused by a potent exotoxin called tetanospasmin produced by gram positive organism Clostridium tetani 2. Tetanus is the only vaccine-preventable disease which is not communicable and is acquired through environmental exposure to the spores of Clostridium tetani 3.…”

Section: Introductionmentioning

confidence: 99%

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Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital

Sultana¹,

Bari

Faizan³

et al. 2019

Pak J Med Sci

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Objective: To determine the prognostic factors and outcome of tetanus in children of post-neonatal age admitted in the intensive care unit (ICU) of a tertiary care hospital. Methods: This prospective cross sectional study, carried out in the Pediatric ICU of The Children’s Hospital Lahore from Jan 2013 to March 2017. Children of both genders with age range of two months to 16 years diagnosed clinically as tetanus were included. All 132 patients were scrutinized for all possible risk factors, need for mechanical ventilation and outcome. Data was analyzed by SPSS version 20. Results: Mean age of children was 7.5±3.4 years with male predominance (70.5%). Only (38.6%) received three doses of vaccination but none had booster dose. Trauma (43.2%) encompassed maximum predisposing factor followed by ear or nose prick and ear discharge. Mean duration of ICU stay was 20±13.3 days. Mortality rate was (17.4%). Ventilator support was given to (78.8%). Neurological outcome was normal in (82.6%). Trauma, ear or nose prick in girls and ear discharge were significantly associated with poor outcome and death with p-value of <0.001, 0.011 and <0.001 respectively. Other factors associated with poor outcome were need for mechanical ventilation and neurological impairment with p-value of 0.001 and <0.001 respectively. Conclusion: Tetanus is causing our children to suffer from devastating disease. Vaccination status is not satisfactory and along with trauma, ear discharge and ear or nose prick are identifiable risk factors. To combat these issues large scale vaccination and booster doses remains promising option. doi: https://doi.org/10.12669/pjms.35.5.656 How to cite this:Sultana N, Bari A, Faizan M, Sarwar M. Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.656 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 95%

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Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital

Sultana¹,

Bari

Faizan³

et al. 2019

Pak J Med Sci

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“…These regional designations will serve as the basis for reporting the total population living in environmentally suitable areas. Tungiasis occurrences records (n = 86) (please see Supplementary Materials : Table S2 ) were assembled through a search of the literature from 1324–2019 [ 23 , 24 , 25 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , …”

Section: Methodsmentioning

confidence: 99%

Mapping the Geographic Distribution of Tungiasis in Sub-Saharan Africa

Deka

2020

TropicalMed

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The geographic distribution of tungiasis is poorly understood, despite the frequent occurrence of the disease in marginalized populations of low socioeconomic status. To date, little work is available to define the geography of this neglected tropical disease (NTD). This exploratory study incorporated geostatistical modeling to map the suitability for tungiasis transmission in sub-Saharan Africa (SSA). In SSA, environmental suitability is predicted in 44 countries, including Angola, Nigeria, Ghana, Cameroon, Cote de Ivoire, Mali, Ethiopia, the Democratic Republic of the Congo, Kenya, Gabon, Uganda, Rwanda, Tanzania, Zambia, Zimbabwe, Madagascar, and South Africa. In total, an estimated 668 million people live in suitable areas, 46% (304 million) of which reside in East Africa. These evidence-based maps provide vital evidence of the potential geographic extent of SSA. They will help to guide disease control programs, inform policymakers, and raise awareness at the global level. Likewise, these results will hopefully provide decisionmakers with the pertinent information necessary to lessen morbidity and mortality in communities located in environmentally suitable areas.

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“…This chemical causes the impairment of the nerves like motor nerves which are responsible for the control of our muscular movements. This causes spasm [1,2].…”

Section: Introductionmentioning

confidence: 99%

Cognizance about Tetanus among University Students

2019

JGDS

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This project was conducted in order to create awareness about the tetanus among students of Bahauddin Zakariya University. About 77 students took part in this research. Tetanus a bacterial disease which cause serious health complication including nervous spasm and certain muscular complications. This disease also known as lock jaw is not common among the developed countries .But certain cases of it are found in the developing and underdeveloped countries. For the purpose of research a questionnaire was designed and result shows a clear awareness of this disease among the students.

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Clinical profile and outcome of pediatrics tetanus: the experience of a tertiary hospital in Ethiopia

Cited by 12 publications

References 13 publications

Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital

Prognostic factors and outcome of Post-Neonatal Tetanus in an intensive care unit of a Tertiary Care Hospital

Mapping the Geographic Distribution of Tungiasis in Sub-Saharan Africa

Cognizance about Tetanus among University Students

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