Clinical profile and outcome of posterior reversible encephalopathy syndrome (PRES)

Patil, Virendra C.; Agrwal, Vaibhav; Rajput, Amardip; Garg, Rishu; Kshirsagar, Ketan; Chaudhari, Vinit

doi:10.4103/1755-6783.162354

Cited by 4 publications

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“…Most studies show elevated blood pressure in these patients. 15,16 The significant finding in our study is that postpartum state without hypertension was a significant etiological factor than eclampsia. This presentation may be due to endothelial dysfunction leading to disruption of blood brain barrier occurring in postpartum complications like puerperal sepsis, postpartum hemorrhage (PPH).…”

Section: Resultsmentioning

confidence: 48%

Clinical spectrum of patients with posterior reversible encephalopathy syndrome

Pulavarty

Midathala

2020

Int J Adv Med

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Background: Posterior reversible encephalopathy syndrome is a neurological disorder which can present with sudden onset headache, visual disturbances, seizures and altered sensorium which is potentially reversible with early detection and treatment of the precipitating factor. The range of presentations is being constantly widened and this endeavour is a step towards understanding the wide array of presentation and primary etiology.Methods: This is a prospective observational study of 25 patients presenting to a tertiary care hospital with symptoms and imaging features suggestive of PRES. Thorough clinical examination and MRI brain were performed in all patients.Results: Out of the 25 patients, 18 (72%) were females and 7 (28%) were males. Most common symptom was headache (84%) followed by seizures (56%), nausea (40%), visual blurring (36%) and altered sensorium (20%). In patients presenting with seizure, 28.57% had recurrent seizures.The most common precipitating cause was postpartum state without hypertension (40%) followed by accelerated hypertension (28%), eclampsia (16%), chronic kidney disease (12%) and one patient of chronic severe anaemia had PRES following blood transfusion (4%). Most of the patients improved with no residual neurological deficit.Conclusions: Good neurological outcomes can be achieved by early diagnosis and appropriate imaging in patients with PRES. In pregnant and postpartum patients, PRES should be always considered even with normal blood pressure. Rapid correction of chronic severe anaemia is a rare but preventable cause of PRES.

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Section: Resultsmentioning

confidence: 48%

Clinical spectrum of patients with posterior reversible encephalopathy syndrome

Pulavarty

Midathala

2020

Int J Adv Med

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“…Although reversible by definition, secondary complications, such as status epilepticus, intracranial hemorrhage, and massive ischemic infraction, can cause substantial morbidity and mortality. 12 Our study of 120 patients were maximum numbers of cases 98 (81.66%) were seen in females in the age group of 21-40 years. This correlates well with a similar study by Fugate et al (65%).…”

Section: Discussionmentioning

confidence: 69%

“…11 Mean age of onset in the present study was 28.64 years which is comparable with Patil VC et al study (29.90 years). 12 The most common clinical presentation was seizures, seen in 94 patients (78.3%), including 76 with generalised tonic clonic seizures, 13 with focal seizures and 5 with status epilepiticus. These findings are comparable with Fugate et al study (74%).…”

Section: Discussionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings: a study from tertiary care hospital

2016

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“… 1 In the present study, the mean age of onset is 38.6 years, which is comparable with other studies. 4 …”

Section: Discussionmentioning

confidence: 99%

“…5 Similar results were also shown in other studies. 2 – 4 In contrary, some studies have shown drugs-toxins and autoimmune disorders as more common underlying etiologies. 13 – 15 The difference in underlying etiologies of PRES is likely to be related to differences in patient profile of various centers.…”

Section: Discussionmentioning

confidence: 99%

Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India

Goyal¹,

Jeswani²

2022

Indian Journal of Critical Care Medicine

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A bstract Background Posterior reversible encephalopathy syndrome (PRES) is a reversible condition. The Main pathological feature is vasogenic cerebral edema with predominant involvement of posterior part of the cerebrum. Clinical symptoms range from headache, seizure, and vision loss. We evaluated the clinicoradiological features of patients with PRES and their clinical outcome. Materials and methods A retrospective study with 30 cases from January 2014 to May 2017. Results Of thirty patients, 18 were females and twelve patients were male. The Mean age of the patients was 38.6 years. The most common presentation was seizure (66.6%) followed by altered mental status (53.3%) and headache (40%). The Main comorbid illnesses in our study were renal disease (36.7%), hypertension (23.3%), eclampsia, and postpartum sepsis (26.7%). The Most common site was the occipito-parietal region in the magnetic resonance imaging brain (66%). Atypical presentation involved the temporal lobe (16%), basal ganglia (6%), and microhemorrhage (6%). The Outcome was good with 20% mortalities. Conclusion PRES is a reversible condition and has a good outcome in most patients. In our study, seizure was the most common presentation and renal disease is the most common comorbid illness. How to cite this article Goyal G, Jeswani J. Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India. Indian J Crit Care Med 2022;26(4):501–505.

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Clinical profile and outcome of posterior reversible encephalopathy syndrome (PRES)

Cited by 4 publications

References 0 publications

Clinical spectrum of patients with posterior reversible encephalopathy syndrome

Clinical spectrum of patients with posterior reversible encephalopathy syndrome

Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings: a study from tertiary care hospital

Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India

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