Clinical profile and outcome of dengue fever in hospitalized children of South Rajasthan, India

Jain, Hemant

doi:10.18203/2349-3291.ijcp20161035

Cited by 18 publications

(39 citation statements)

References 8 publications

(12 reference statements)

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“…[13]. In the study by Jain et al [11]35 (53%) were boys and 30 (47%) were girls. Male to female ratio was 1.16:1.…”

Section: Discussionmentioning

confidence: 90%

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Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana

Sastry¹,

Padmavathi²

2019

Int J Pediatr Res

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Introduction:The aim of the study was to determine the clinical and hematological profile in patients with Dengue fever. Materials and Methods: This was a prospective study done at Malla Reddy Medical College for Women, Telangana, for a period of six months. A total of 110 cases of dengue infection were studied. The patient demographics, clinical symptoms, hematological characteristics such as hemoglobin, total leucocyte count, platelet count, serological studies and abdominal ultrasound findings were noted. Results: In the present study, 85/110 (77.2%) cases were of dengue fever, 20/110 (18.1%) were dengue hemorrhagic fever (DHF) and 05/110 (4.5%) were of dengue shock syndrome (DSS). Patient age ranged from 0-12 years. Majority, 55/110 (50%) were among 6-8 years. Males were affected more than females (59% boys and 41% were girls). Moderate thrombocytopenia was seen in 54.5% of cases and raised hematocrit (>47%) was observed in 22.7% cases. Most of the cases 75 (68.1%) were noted in September and October. Conclusion: Dengue is a common viral infection which may have serious consequences especially in children. Simple haematological parameters along with serological tests and ultrasound of abdomen are helpful in the diagnosis and appropriate management of these patients. managed, may lead to rapid death, particularly in children [5,6]. Dengue is an acute febrile disease caused by a flavivirus with four known serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). The four serotypes can lead to variable clinical presentations, ranging from asymptomatic to severe forms [7].Children represent more peculiar characteristics since dengue diagnosis, and recognition of severe forms are both more difficult to find than in adults. The common signs and symptoms are fever, headache, myalgia, arthralgia, and bleeding manifestations. The exact clinical profile is necessary for the patient's management and hence, crucial for saving life [8]. Aim of the study:To study clinical and hematological profile in children with dengue fever.

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“…[13]. In the study by Jain et al [11]35 (53%) were boys and 30 (47%) were girls. Male to female ratio was 1.16:1.…”

Section: Discussionmentioning

confidence: 90%

“…The mean age of the study population was estimated to be 7.8±3.2 years. In the study by Jain et al [11] the most common age group was between 5 to 10 years (46%) followed by 1-5 year age group. Infants were only 7.6% and the youngest one was 7 months old.…”

Section: Discussionmentioning

confidence: 93%

Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana

Sastry¹,

Padmavathi²

2019

Int J Pediatr Res

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“…Pleural effusion in DF, which occurs probably due to increased vascular permeability, plasma leakage, abnormalities of hemostasis and protein-losing shock syndrome [29], was observed in 100% of DHF and 1.67% of DF patients. Variable incidence of pleural effusion was reported in previous reports [18,28,29].…”

Section: Discussionmentioning

confidence: 70%

“…Hypotension was present in 27 cases (22%) (one DSS, two DHF). Other studies reported hypotension in 65% and 5% of cases [22,28], respectively.…”

Section: Discussionmentioning

confidence: 86%

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Clinical spectrum of dengue fever in hospitalized children in Mukalla city, Yemen after the attack of Chapala cyclone Nov. 2015

Dahman¹,

Hatem²

2017

IJMDC

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Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City

Shultana¹,

Rahman²,

Baki³

et al. 2019

AJP

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Dengue is a self-limiting acute mosquito born disease caused by Dengue virus. Dengue infections may be asymptomatic or can result in a wide spectrum of disease severity ranging from an influenza-like illness (Dengue fever) to the life-threatening Dengue hemorrhagic fever (DHF)/Dengue shock syndrome (DSS). We aimed to analyze the variation in clinical spectrum, outcome and possible risk factors for fatality among Dengue infected children. This was an observational study carried out over a period of one year involving 89 children up to 15 years of age. Upon clinical suspicion Dengue was confirmed by NS 1 antigen and/or Dengue antibody IgM, IgG. Positive Dengue cases were enrolled & interviewed and the information obtained related to the risk factors, clinical presentation, pattern of Dengue infection and outcome were documented in the pre-structured questionnaire. Among the 89 studied children the highest percentage (51.68%) was between 0-5 year and male female ratio was 1.2: 1. Mosquito net was not used by (74.15%) children and there was source of stagnant water in/near the house of (13.48%) children. Fever was present in (100%), rash in (48.31%), nausea/vomiting in (37.07%), headache in (12.35%), myalgia/arthralgia/backache (13.48%), retro orbital pain (1.12%) and abdominal pain in (23.59%) patient. Epistaxis was the commonest (70%) form of bleeding. CNS involvement was in the form of restlessness/irritability (19.10%), altered sensorium (2.24%) and convulsion. Pleural effusion was commoner than ascites; (25.84%) and (12.35%) respectively. Among the enrolled children Dengue fever was (74.15%), Dengue hemorrhagic fever (6.74%) and Dengue shock syndrome (19.10%). Two patients died out of 17 from Dengue shock syndrome which was (11.76%). World Health Organization (WHO) guideline based management should be applied in assessing and managing Dengue cases to reduce mortality rate. Public awareness should be widened to prevent Dengue.

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Clinical profile and outcome of dengue fever in hospitalized children of South Rajasthan, India

Cited by 18 publications

References 8 publications

Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana

Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana

Clinical spectrum of dengue fever in hospitalized children in Mukalla city, Yemen after the attack of Chapala cyclone Nov. 2015

Dengue Infection in Children: Clinical Profile and Outcome in Dhaka City

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