Clinical Profile and Endoscopic Findings in Patients undergoing Colonoscopy at a Tertiary Care Centre of Central Nepal

Bhattarai, Subash; Acharya, Ramesh Raj

doi:10.3126/jcmsn.v16i2.28660

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…Our results were supported by Bhattarai and Acharya [7] who revealed that the commonest indications for performing colonoscopy were chronic diarrhea, altered bowel habits, chronic abdominal pain and bleeding per rectum. Furthermore, Benhamdane et al [8] revealed that the most common indications for pathological colonoscopy were: rectal bleeding, diarrhea, constipation, iron deficiency anemia and melena.…”

Section: Discussionsupporting

confidence: 87%

Colonoscopic Findings in Patients Attended At Al Azhar Assiut University Hospital Endoscopy Unit in the Last Two Years

Tag-El Deen,

Ali,

Sawy

2024

International Journal of Medical Arts

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Section: Discussionsupporting

confidence: 87%

Colonoscopic Findings in Patients Attended At Al Azhar Assiut University Hospital Endoscopy Unit in the Last Two Years

Tag-El Deen,

Ali,

Sawy

2024

International Journal of Medical Arts

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“…The sample size was calculated based on the standard formula 9 for cross-sectional studies n =Z 2 a/2 *P*(1−P)/d 2 , where Z a/2 was 1.96 for 95% level of confidence, P is the estimated proportion of prevalence of primary outcome and d is the desired level of precision which was set at 0.02. The prevalence proportion (P) was considered to be 6.48% 4 , and thus, the total sample size study required was 642, including an additional 10% to avoid errors. A convenience sampling method was implemented to select participants.…”

Section: Methodsmentioning

confidence: 99%

“…Despite the importance of colonoscopy in clinical practice, only a few studies have described patients undergoing colonoscopy in Nepal 4 – 7 . In this study, we aim to evaluate the demographic characteristics, clinical presentation, colonoscopy observations and histological findings of patients undergoing colonoscopy by analyzing the records at a tertiary care hospital in Nepal.…”

Section: Introductionmentioning

confidence: 99%

Demographic and clinical profile of patients undergoing colonoscopy at a tertiary care center in Nepal: a retrospective cross-sectional study

Sharma,

Sapkota,

Gurung

et al. 2024

Annals of Medicine &Amp; Surgery

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Background: Colonoscopy is widely used as a tool for diagnosis, screening and treatment of various pathologies in the rectum, colon, and terminal ileum. The aim of this study is to evaluate the demographic, clinical, and histological parameters of the records of patients undergoing colonoscopy at a tertiary care hospital in Nepal. Materials and methods: This retrospective cross-sectional study included the hospital records of all patients who underwent colonoscopy from 2015 to 2019 in a tertiary care centre in Nepal. Results: A total of 1255 records were included in the study. The mean and standard deviation of age were 43.8 and 19 years, respectively. Among the total study population, 61.9% were males and 38.1% were females. Common indications for colonoscopy included lower gastrointestinal bleeding (27.7%), altered bowel habit (26.9%) and persistent or recurrent abdominal pain (17.3%). Only 3% of the patients who underwent colonoscopy had inadequate bowel preparation. The overall diagnostic yield of colonoscopy was 57.5%. Findings during colonoscopy included colorectal polyp (19.4%), internal haemorrhoids (8.2%) and colitis (6.5%). Having an age of 50 or more years was significantly associated with the presence of colorectal adenocarcinoma (P=0.017, χ2 test) with an odds ratio of 2.35 (95% CI: 1.14, 4.89). Furthermore, having a female sex was found to be significantly associated with the presence of colorectal adenocarcinoma (P=0.012, χ2 test) with an odds ratio of 2.43 (95% CI: 1.19, 4.97). Conclusion: In the authors’ study, a smaller proportion of the colonoscopies was aimed at screening for colorectal carcinoma (CRC), when compared to studies in developed countries. The sex predisposition of CRC in the authors’ study is in contrast to the global trend. The authors recommend conducting studies to determine the risk factors and need for CRC screening in the Nepalese population.

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Histomorphological Distribution and Endoscopic Correlation of Colonoscopic Biopsies in Rural North India

Sharma

Sangwan²,

Sharma

2021

Global Journal for Research Analysis

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Colonoscopy provides information on the natural history and complications of many lesions. Biopsy forceps provide the opportunity to obtain multiple samples for evaluating the pathogenesis of the disease. Pathologist plays an important role in the diagnosis and management of patients with colitis. It is further made use of for GI cancers that are amongst the commonest malignancies worldwide. This prospective study of 300 cases included colonoscopic biopsies received in the department of pathology. We found out of 300 cases, 237 were non-neoplastic, 12 cases were benign and 51 were neoplastic. Out of the non-neoplastic cases, maximum was ulcerative colitis (UC); followed by acute colitis and chronic colitis. The benign lesions included tubular adenoma and tubulo-villous adenoma. Amongst the malignant ones, moderately differentiated adenocarcinomas predominated. On endoscopic histopathological correlation, non neoplastic lesions, benign and malignant lesions correlated 71%, 100% and 88% respectively. Conclusion of the study advocated that comprehensive histopathological study of the colonoscopic biopsy specimens should be done in constant correlation with the clinical and colonoscopic procedures for follow up of inflammatory diseases like UC and CD as well as early recognition of carcinomas.

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Clinical Profile and Endoscopic Findings in Patients undergoing Colonoscopy at a Tertiary Care Centre of Central Nepal

Cited by 3 publications

References 9 publications

Colonoscopic Findings in Patients Attended At Al Azhar Assiut University Hospital Endoscopy Unit in the Last Two Years

Colonoscopic Findings in Patients Attended At Al Azhar Assiut University Hospital Endoscopy Unit in the Last Two Years

Demographic and clinical profile of patients undergoing colonoscopy at a tertiary care center in Nepal: a retrospective cross-sectional study

Histomorphological Distribution and Endoscopic Correlation of Colonoscopic Biopsies in Rural North India

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