2020
DOI: 10.1002/ccr3.3719
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Clinical presentations and outcomes of COVID‐19 infection in sickle cell disease patients: Case series from Komfo Anokye teaching hospital, Ghana

Abstract: Patients with sickle cell disease and COVID‐19 may not have a more dire outcome than the general population. Nevertheless, they may present with acute chest syndrome and other sickle cell crises which should be aggressively managed.

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Cited by 8 publications
(7 citation statements)
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References 27 publications
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“… n/a 0 (0) Fronza et al [ 112 ] Italy 1 (0/1) 44 n/a BT (1) Patient recovered and was discharged after severe anemia and acute lung failure. n/a 0 (0) Hardy et al [ 113 ] Ghana 3 (0/3) 28 HbSS (1), HbSC (2) BT (2) One had severe COVID-19 pneumonia. Two had severe SCD crisis.…”
Section: Patients With Covid-19 and Sickle Cell Diseasementioning
confidence: 99%
“… n/a 0 (0) Fronza et al [ 112 ] Italy 1 (0/1) 44 n/a BT (1) Patient recovered and was discharged after severe anemia and acute lung failure. n/a 0 (0) Hardy et al [ 113 ] Ghana 3 (0/3) 28 HbSS (1), HbSC (2) BT (2) One had severe COVID-19 pneumonia. Two had severe SCD crisis.…”
Section: Patients With Covid-19 and Sickle Cell Diseasementioning
confidence: 99%
“…When compared with healthcare professionals infected with COVID-19 in the same age group, it is seen that patients have more comorbid conditions and develop more pneumonia as expected [23][24][25]. It was noteworthy that in addition to the comorbid state, one-third of the patients used ACE inhibitors for proteinuria or cardiac reasons.…”
Section: Discussionmentioning
confidence: 94%
“…25 In a large population-based screening study in Bahrain, AbdulRahman et al 26 reported no difference in infection rate, clinical course, and viral clearance for SCD patients compared with those without SCD. Similarly, Arlet et al 20 reported no increased mortality or morbidity risk in a large cohort of patients in France, Chakravorty et al 27 reported a mild clinical course, and favorable outcomes in a cohort of patients in the United Kingdom, and Hardy et al 24 reported that SCD patients in Ghana did not seem to have a worse prognosis than patients without SCD.…”
Section: Discussionmentioning
confidence: 97%