Clinical presentation of soft-tissue infections and its management: A study of 100 cases

Abstract

Background:Soft-tissue infections vary widely in their nature and severity. A clear approach to the management must allow their rapid identification and treatment as they can be life-threatening.Objective:Clinical presentation of soft-tissue infections and its management.Materials and Methods:A prospective study based on 100 patients presenting with soft-tissue infections was done. All the cases of soft-tissue infections were considered irrespective of age, sex, etiological factors, or systemic disorders. The findings were evaluated regarding the pattern of soft-tissue infections in relation to age and sex, clinical presentation, complications, duration of hospital stay, management, and mortality.Results:The most commonly involved age group was in the range of 41–60 years with male predominance. Abscess formation (45%) was the most common clinical presentation. Type 2 diabetes mellitus was the most common associated comorbid condition. Staphylococcus aureus was the most common culture isolate obtained. The most common complication seen was renal failure. Patients with surgical site infections had maximum duration of stay in the hospital. About 94% of the cases of soft-tissue infections were managed surgically. Mortality was mostly encountered in the cases of complications of cellulitis.Conclusion:Skin and soft-tissue infections are among the most common infections encountered by the emergency physicians. Ignorance, reluctance to treatment, economic constraints, and illiteracy delay the early detection and the initiation of proper treatment. Adequate and timely surgical intervention in most of the cases is of utmost importance to prevent the complications and reduce the mortality.

An Increasing Trend in the Antimicrobial Resistance of Bacterial Isolates from Skin and Soft Tissue Infections in a Tertiary Care Hospital

“…Higher number of samples from surgery department has been observed in many studies (Roopa et al) 7 . The most common age group affected by pyogenic infection in our study was 41-50 years and there was a predominance of males(75.7%) over female patients(18.9%).This was comparable to a study by Singh et al 8 and Roopa et al 7 .…”

“…30 Among hospitalized patients, the estimated prevalence of SSTIs is 7%-10% 29 . In South India, incidence is about 2% 2 and the mortality rate ranges from 4% (Singh et al, North India) 8 to 14% (Abhilash KP et al, South India) 2 Even with advances in infection control practices like improved operating room ventilation, sterilization methods, surgical technique and availability of antimicrobial prophylaxis, Surgical Site Infections (SSIs) remain a substantial cause of morbidity, prolonged hospitalization and mortality rate of 3% globally 24 . Surgical-site infection (SSI) is an infection of the skin or deep-space occurring at the incision or in the field of an invasive procedure within 30 days after operation (1 year for an implant) 24 .…”

Microbial Profile and Antibiogram Pattern Analysis of Skin and Soft Tissue Infections at a Tertiary Care Center in South India

“…Non fermenting GNB (Pseudomonas spp and Acinetobacter spp) showed high susceptibility to tetracycline (84.9%), Meropenem (67.3%), piperacillin-tazobactam (67.2%), Imipenem (64.9%) and amikacin (60.2%). There is a decrease in susceptibility observed with beta lactam antibiotics compared to data from similar studies in previous years 20,21,28,29 Among the Gram-negative bacilli isolated the overall resistance rates were highest with Acinetobacter spp followed by Klebsiella spp. Similar results were observed with studies from various parts of India 21,[30][31][32] .…”

Factors for a clinical prediction score to determine complication development after cellulitis diagnosis in adult patients

“…3 Apart from the patient's comorbidities, several elements are regarded as risk factors for hospitalization, such as, increased age, immunode ciency status, and area of skin involved. 4 The New England Journal of Medicine 5 suggests obtaining blood cultures in patients with cellulitis who have systemic symptoms (fever or chills), lymphedema with superimposed cellulitis, or tissue exposure to a non-sterilized body of water. It also suggests admitting patients who have failed outpatient management or those with rapidly spreading infection.…”