Clinical presentation and prognostic factors affecting surgical outcomes of secondary macular holes after retinal vein occlusions

Mishra, Chitaranjan; Kannan, Naresh Babu; Sen, Sagnik; Singh, Khushwant; Damodaran, Sourav; Kohli, Piyush; Kumar, Karthik; Rajan, Renu P; Baliga, Girish; Ramasamy, Kim

doi:10.1007/s10792-020-01465-7

Cited by 5 publications

(5 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, all these potential risk factors can be found in our case. It has been reported that MH secondary to RVO may achieve satisfactory results after surgery [2,3]. In agreement with these studies, our case also showed favorable morphological outcomes and improved visual function following PPV surgery.…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Full-Thickness Macular Hole After Intravitreal Conbercept Injection in Branch Retinal Vein Occlusion

Xie¹,

Zhu²,

Yan³

et al. 2023

Cureus

View full text Add to dashboard Cite

This article reports a case of macular hole (MH) formation following intravitreal conbercept injection for branch retinal vein occlusion (BRVO). A 70-year-old male received three consecutive intravitreal injections of conbercept for the treatment of macular edema secondary to BRVO in his left eye. Due to the outbreak of the COVID-19 epidemic, the patient was lost to follow-up. At two months follow-up, a full-thickness MH was detected by fundoscopic and optical coherence tomography examination. Fortunately, the MH was successfully closed after pars plana vitrectomy. MH is a rare complication following intravitreal injections for RVO, which should be considered by clinicians.

show abstract

Section: Discussionsupporting

confidence: 92%

“…Macular edema is a common complication of retinal vein occlusion (RVO), which can cause severe visual impairment [1,2]. At present, anti-VEGF (aVEGF) injection is the first-line treatment with favorable results, however, some adverse effects have been reported in a few cases, including macular hole (MH) [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Full-Thickness Macular Hole After Intravitreal Conbercept Injection in Branch Retinal Vein Occlusion

Xie¹,

Zhu²,

Yan³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…However, the clinical characteristics and surgical outcomes of secondary FTMH are different. [ 4 9 15 16 17 ] MH in eyes with PDR TRD is formed due to perimacular tangential traction exerted by the FVP(s). As a result, detachment around the MH is usually larger than the simple cuff seen in the idiopathic FTMH.…”

Section: Discussionmentioning

confidence: 99%

“…As a result, detachment around the MH is usually larger than the simple cuff seen in the idiopathic FTMH. [ 2 3 8 16 17 18 19 ]…”

Section: Discussionmentioning

confidence: 99%

Surgical outcome of full-thickness macular hole secondary to tractional retinal detachment in proliferative diabetic retinopathy

Ramasamy

Babu

Kohli

et al. 2021

Indian Journal of Ophthalmology

Self Cite

View full text Add to dashboard Cite

Purpose: To evaluate the surgical outcome of full-thickness macular hole (FTMH) secondary to active fibrovascular proliferation (FVP) and tractional retinal detachment (TRD) in eyes with proliferative diabetic retinopathy (PDR), and factors influencing the outcome. Methods: This retrospective study included the patients who underwent vitrectomy for FTMH secondary to PDR TRD from 2016 to 2020. Anatomical and visual outcomes were analyzed after six months along with the factors predicting the final outcome and duration of subretinal fluid (SRF) resolution. Results: Group A (macula-off combined RD, i.e., tractional and rhegmatogenous) included 10 eyes, while group B (macula-threatening TRD) included eight eyes. The mean best-corrected visual acuity improved from logMAR 1.21 (Snellen equivalent: 20/324) to logMAR 0.76 (Snellen equivalent: 20/115) ( P = 0.008). Seventeen patients gained ≥1 line(s) of vision. Mean visual gain in groups A and B was 3.7 ± 1.9 and 1.9 ± 1.1 lines, respectively ( P = 0.051). MH closed in 88.9% eyes. Type 1 anatomical closure was achieved in 88.9% of eyes. At 6 months, SRF and central macular thickness reduced from 479.6 ± 512.5 μm to 11.4 ± 23.5 μm ( P = 0.002) and 874.3 ± 422.6 μm to 207.6 ± 81.7 μm ( P = 0.0002), respectively. Finally, macular SRF resolved in all the patients. The mean duration for complete SRF resolution was 4.9 ± 3.2 months. Eyes with a shorter duration of diabetes mellitus (rho = −0.49, P = 0.040) and macula-off combined RD ( P = 0.048) took a longer time for complete SRF resolution. Conclusion: Good anatomical and visual outcomes can be achieved in eyes with PDR TRD-associated FTMH. The residual macular SRF resolves slowly after the surgery and extra intervention is not required. Macula-off combined RD is associated with worse outcome and a slower SRF resolution rate.

show abstract

“…Other retinal pathologies may indirectly cause macular holes. For example, macular holes have been reported in association with retinal vein occlusions, diabetic retinopathy, hypertensive retinopathy, and retinal artery macroaneurysm (1)(2)(3)(4) .…”

Section: Introductionmentioning

confidence: 99%

A full thickness macular hole following severe preeclampsia: a case report

Özçalışkan¹,

Artunay²,

Erdoğan³

et al. 2023

ABO

View full text Add to dashboard Cite

We report a case of a young woman presenting with decreased vision in the right eye. One month earlier, she developed severe preeclampsia at 22 weeks of gestation and the pregnancy was terminated. Fundus examination revealed cotton wool spots and hard exudates in the macula bilaterally, with a yellow spot at the center of the fovea in the right eye. Optic coherence tomography showed a full thickness macular hole with elevated cystoid edges in the right eye. The patient was diagnosed with macular hole secondary to preeclampsia and followed up for spontaneous closure. One month after the first visit, surgical intervention was suggested due to declining vision. Three months later, the patient agreed to surgery. She underwent pars plana vitrectomy with a temporal inverted internal limiting membrane flap and C3F8 endotamponade, which provided anatomic and visual improvement.

show abstract

Clinical presentation and prognostic factors affecting surgical outcomes of secondary macular holes after retinal vein occlusions

Cited by 5 publications

References 30 publications

Full-Thickness Macular Hole After Intravitreal Conbercept Injection in Branch Retinal Vein Occlusion

Full-Thickness Macular Hole After Intravitreal Conbercept Injection in Branch Retinal Vein Occlusion

Surgical outcome of full-thickness macular hole secondary to tractional retinal detachment in proliferative diabetic retinopathy

A full thickness macular hole following severe preeclampsia: a case report

Contact Info

Product

Resources

About