Clinical presentation and outcomes of cholecystectomy for acute cholecystitis in patients with diabetes - A matched pair analysis. A pilot study

Łącka, Monika; Obłój, Paweł; Spychalski, Piotr; Łaski, Dariusz; Rostkowska, Olga; Wieszczy, Paulina; Kobiela, Jarek

doi:10.1016/j.advms.2020.08.001

Cited by 3 publications

(5 citation statements)

References 24 publications

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“…In 2014, a retrospective analysis revealed the probability of developing a surgical site infection is significantly higher in patients with diabetes who delayed their cholecystectomy for more than 24 hours following admission, but not systemic infections, and it was not reported in the nondiabetics [60]. Longer surgery time due to long hospital stays and more frequent complications including more SSI, more norepinephrine need inhospital time due to cardiac deficiency, more requiring transfer to the ICU because of cardiac arrest in the diabetic are observed [57]. A history of diabetes increases the risk of renal failure, cardiovascular events, and even mortality following cholecystectomy for acute cholecystitis.…”

Section: Complicationmentioning

confidence: 98%

“…It is expected that diabetics are more likely to have some abnormal postoperative complications than those who don't suffer from diabetes melitus [56]. According to Monika Lacka et al [57] in 2020 the association between diabetes and the acute cholecystitis is independent and diabetic patients experience more frequent complications after cholecystectomy [57]. Of course, it should be noted that some studies have come to the opposite conclusion.…”

Section: Complicationmentioning

confidence: 99%

“…Regarding the difficulty of surgery, a study in Iran which conducted by Sarmadi et al [64] demonstrates laparoscopic technique has been more difficult for patients with diabetes [64]. It has been identified as a cause of conversion from the laparoscopic to the open surgery cholecystectomy in some researches and not in others [57]. Generally, most of studies have mentioned different postoperative outcomes between diabetics and nondiabetics and more and severe complications in diabetics for example SSI.…”

Section: Complicationmentioning

confidence: 99%

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Diabetes and Cholecystectomy: Is There a Relation?

Olangian-Tehrani

2023

JCSR

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The association between diabetes and cholecystectomy is debatable, as diabetes or cholecystectomy may be risk factors for each other. In this review, we look at the incidence rate, mechanisms, and complications of cholecystectomy in diabetic individuals and healthy ones and we also compare cholecystectomy in both to see whether diabetes is a risk factor for cholecystectomy or diabetes might lead to cholecystectomy, or both are contributed.

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Section: Complicationmentioning

confidence: 98%

Section: Complicationmentioning

confidence: 99%

Section: Complicationmentioning

confidence: 99%

See 1 more Smart Citation

Diabetes and Cholecystectomy: Is There a Relation?

Olangian-Tehrani

2023

JCSR

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“…Contrary to the famous quote of William Mayo stating that 'there is no innocent gallstone', recent studies on the natural history of cholelithiasis indicate that less than one-third of the patients having gallstones will eventually become symptomatic (2)(3)(4). Although the same observation applies in patients suffering from DM, these tend to develop more severe complications, have longer hospital stays, and higher fatality rates (5). As a result, before the era of evidence-based medicine, for numerous generations of surgeons the logic-driven temptation to recommend prophylactic cholecystectomies in this category of patients became a perpetuated paradigm (6).…”

Section: Introductionmentioning

confidence: 96%

Clinical and therapeutic features of acute cholecystitis in diabetic patients

et al. 2021

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The present study aimed to compare the clinical, paraclinical, intraoperative findings, and postoperative complications in acute cholecystitis in diabetic patients vs. non-diabetic patients. A 2-year retrospective study was performed on the patients who underwent emergency cholecystectomy for acute cholecystitis between 2017 and 2019 at the 4th Department of Surgery, Emergency University Hospital Bucharest. The diabetic subgroup numbered 46 eligible patients and the non-diabetic one 287 patients. Demographics, the severity of the clinical forms, biological variables (including white cell count, urea, creatinine, coagulation and liver function tests) comorbidity status, surgical approach, postoperative complications, and hospital stay were analyzed. Statistical analyses were performed to assess comparative results between the aforementioned data (SPSS V 13.0). The CCI and ASA risk classes were increased in the diabetic group, with 34.78% of patients having 3 or more associated comorbidities. No statistically significant associations were demonstrated between diabetes and the severity of the cholecystitis and risk for conversion. Postoperatively both minor complications such as surgical site infections and major cardiovascular events were more common in the diabetic subgroup (P=0.0254), well associated with the preoperative status and baseline cardiovascular comorbidities.Laparoscopic cholecystectomy is a safe procedure for diabetic patients, which can provide the best outcomes, by decreasing the risks of surgical wounds. Attentive perioperative care and good glycemic control must be provided to minimize the risk of complications.

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“…Although the same observation applies in patients suffering from diabetes mellitus (DM), these patients tend to develop more severe complications, have longer hospital stays, and suffer higher fatality rates [20]. Some studies mention a higher degree of gallbladder distension and an increased wall tension secondary to kinetic disorders caused by microangiopathy and diabetic neuropathy.…”

Section: Introductionmentioning

confidence: 99%

Pyogenic Liver Abscess Complicating Acute Cholecystitis: Different Management Options

Paramythiotis

Karakatsanis²,

Karlafti³

et al. 2022

Medicina

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Acute cholecystitis, which is usually associated with gallstones is one of the most common surgical causes of emergency hospital admission and may be further complicated by mural necrosis, perforation and abscess formation. Perforation of the gallbladder is a relatively uncommon complication of acute cholecystitis (0.8–3.2% in recent reviews). The intrahepatic perforation causing a liver abscess is an extremely rare condition, anecdotally reported in the scientific literature, even in the rare types of subacute or acute perforation. Liver abscess caused by gallbladder perforation can be a life-threatening complication with a reported mortality of 5.6%. The treatment of synchronous pyogenic liver abscess and acute cholecystitis may be challenging. We reported three cases of liver abscess due to acute cholecystitis in which different therapeutical approaches were employed. The first case was treated with antibiotics and interval laparoscopic cholecystectomy; the second case was treated with emergency cholecystectomy; and the third case with percutaneous aspiration of the abscess only. The appropriate therapeutical method in these cases depends on the patient’s clinical condition, the on-site expertise that is available in the hospital, and the experience of the surgeon.

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Clinical presentation and outcomes of cholecystectomy for acute cholecystitis in patients with diabetes - A matched pair analysis. A pilot study

Cited by 3 publications

References 24 publications

Diabetes and Cholecystectomy: Is There a Relation?

Diabetes and Cholecystectomy: Is There a Relation?

Clinical and therapeutic features of acute cholecystitis in diabetic patients

Pyogenic Liver Abscess Complicating Acute Cholecystitis: Different Management Options

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