Clinical predictors of fetal and maternal outcome in Chinese patients with systemic lupus erythematosus

Mok, MY; Leung, P. Y.; Lao, Tth; Lo, Ymd; Chan, T M; Wong, Wing‐Tak; Lau, CS

doi:10.1136/ard.2004.022442

Cited by 23 publications

(20 citation statements)

References 10 publications

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“…We found lower aPLs and LAC in women with CLE than in those with SLE (19 vs. 48%), which importantly could be a second factor explaining the higher pregnancy loss in the SLE group. Previous studies have reported that 10–60% of SLE patients have aPLs and/or LAC. The association between these antibodies and pregnancy loss, IUGR and PE has been documented .…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have reported that 10–60% of SLE patients have aPLs and/or LAC. The association between these antibodies and pregnancy loss, IUGR and PE has been documented . Lack of sound implantation and development of placental vasculature thrombosis are possible mechanisms .…”

Section: Discussionmentioning

confidence: 99%

“…The sample size was calculated based on previous studies showing a pregnancy loss rate of 25–83% in SLE patients compared with healthy women without a previous history of repeated abortions, where the pregnancy loss ranges between 12 and 19% . As we found no previous studies addressing pregnancy outcome in a selected CLE population, we assumed that those patients might have 20% lower risk of pregnancy loss than SLE.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Does cutaneous lupus erythematosus have more favorable pregnancy outcomes than systemic disease? A two‐center study

Hamed

Ahmed

Alzolibani

et al. 2013

Acta Obstet Gynecol Scand

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Does cutaneous lupus erythematosus have more favorable pregnancy outcomes than systemic disease? A two‐center study

Hamed

Ahmed

Alzolibani

et al. 2013

Acta Obstet Gynecol Scand

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“…Recent reports showed an improved maternal and foetal outcomes in lupus pregnancies from developed countries [1][2][3][4][5]. Reports of lupus pregnancies among Asian patients are limited [6][7][8][9][10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Systemic lupus erythematosus pregnancies: the Sarawak experience and review of lupus pregnancies in Asia

et al. 2010

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We performed a cross-sessional study of all systemic lupus erythematosus (SLE) pregnancies during a 4-year period (2006-2009) to describe the clinical features, maternal and foetal outcomes in our centre. There were 48 pregnancies in 44 women with SLE. Our patients have a mean age of 30.0 years (SD 6.36) and a mean disease duration of 40.67 months (SD 48.23). Our patients have complicated pregnancies: 32.7% have SLE flares, 17.3% have preeclampsia and 48.9% needed caesarean sections. There were 20.0% foetal losses and 17.8% preterm deliveries in our patients. SLE flares contributed to 60.0% of foetal losses in our patients. Lupus pregnancies in our centre generally have a good maternal and foetal outcome comparable to developed countries in Asia. The low incidence of APS, the high usage of hydroxychloroquine and the high SLE remission rate in our patients prior to conceptions contributed to the good outcome.

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“…Mok et al studied 91 pregnancies, reporting that antiphospholipid antibodies were more prevalent in patients with recurrent miscarriages and the strongest predictive factor was the presence of lupus anticoagulant. 4 One-third of the patients have APS secondary to systemic lupus erythematosus (SLE). This high percentage of the disease is due the selective population studied.…”

Section: 23mentioning

confidence: 99%

The Fetomatemal Outcome of Autoimmune Diseases in Pregnancy

Mohan¹

2018

jmscr

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Clinical predictors of fetal and maternal outcome in Chinese patients with systemic lupus erythematosus

Cited by 23 publications

References 10 publications

Does cutaneous lupus erythematosus have more favorable pregnancy outcomes than systemic disease? A two‐center study

Does cutaneous lupus erythematosus have more favorable pregnancy outcomes than systemic disease? A two‐center study

Systemic lupus erythematosus pregnancies: the Sarawak experience and review of lupus pregnancies in Asia

The Fetomatemal Outcome of Autoimmune Diseases in Pregnancy

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