Clinical predictors of delayed neurological sequelae in charcoal-burning carbon monoxide poisoning

Magnetic resonance imaging for predicting delayed neurologic sequelae caused by carbon monoxide poisoning: A systematic review and meta-analysis

“…Precise prognostic forecast of patients with acute CO poisoning is critical for making further management decisions. In this study, DNS developed in 29.2% of our patients, which is consistent with previous research [ 6 , 14 , 20 ] Our findings showed that the AUC of MRI for predicting DNS caused by CO poisoning was 0.83 (95% CI: 0.79–0.86), with 72% sensitivity and 80% specificity, which indicate that MRI is a good prediction method.…”

Derivation and Validation of a Score for Predicting Poor Neurocognitive Outcomes in Acute Carbon Monoxide Poisoning

“… 7 , 12 , 20 , 41 , 42 , 43 Although serum lactate and troponin I levels were reported as risk factors in previous studies, 19 , 44 , 45 in this study, neither was associated with outcome. A few studies, such as a 2021 study by Sert et al, 17 have suggested that acute brain damage detected with brain magnetic resonance imaging is associated with poor prognosis, but we excluded brain magnetic resonance imaging, as it cannot be performed early in all hospitals.…”

“…For widespread applicability, we limited variables to known and potential risk factors 6 , 7 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 and commonly used variables in acute co poisoning. We evaluated patient age, sex, poisoning intentions, co source (ie, charcoal, oil and gas, or fire), drug coingestion, GCS score at the site of rescue or ED arrival, comorbidities (ie, diabetes, hypertension, cardiovascular disorder, and psychiatric disease), current smoking status and alcohol coingestion, interval of loss of consciousness, shock, seizure, and application of HBO (eAppendix 1 in the Supplement ).…”

“…Clinical and laboratory variables suggested for predicting poor neurocognitive prognosis 6 , 7 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 include older age, underlying cardiovascular disease, any interval loss of consciousness, acidosis, Glasgow Coma Scale (GCS) score, serum creatine kinase level, longer co exposure intervals, serum lactate level, and HBO treatment. As there is no validated simple and accurate clinical scoring model for stratifying patients according to their risk of poor neurocognitive prognosis in early phase, we aimed to develop and validate a simple, accurate clinical scoring model for predicting poor neurocognitive outcomes at 1 month after co poisoning.…”

Optical coherent tomography angiography observation of macular subinternal limiting membrane hemorrhage in CO poisoning: a case report

“…CO is the most common imperceptible but lethal gas. In the United States, CO causes more than 50 000 intoxications, while globally, the mortality rate is 4.6 per million [1][2] . Many studies have focused on CO intoxication damage to the central nervous system and cardiovascular system [3][4] , but the eye remains a neglected organ in CO poisoning.…”