2008
DOI: 10.1038/jp.2008.47
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Clinical practices in neonatal oxygenation: where have we failed? What can we do?

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Cited by 56 publications
(64 citation statements)
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“…4,5 While over the last decades, the main focus of concern regarding possible causes of impaired neurological outcome was on insufficient oxygenation during the perinatal period, there is, based on the work of Ola Saugstad, Maximo Vento and other researchers, increasing concern regarding shortand long-term damage to newborns exposed to high oxygen concentrations in the delivery room. [6][7][8][9][10][11][12][13] It is only recently that the noxious potential of excess oxygen exposure during the resuscitation of near-term or term infants immediately after birth has been recognized. 14,15 It has therefore been proposed to start neonatal resuscitation in the delivery room by administering a lower FiO 2 , a proposal which has been echoed by several international recommendations on neonatal resuscitation.…”
Section: Introductionmentioning
confidence: 99%
“…4,5 While over the last decades, the main focus of concern regarding possible causes of impaired neurological outcome was on insufficient oxygenation during the perinatal period, there is, based on the work of Ola Saugstad, Maximo Vento and other researchers, increasing concern regarding shortand long-term damage to newborns exposed to high oxygen concentrations in the delivery room. [6][7][8][9][10][11][12][13] It is only recently that the noxious potential of excess oxygen exposure during the resuscitation of near-term or term infants immediately after birth has been recognized. 14,15 It has therefore been proposed to start neonatal resuscitation in the delivery room by administering a lower FiO 2 , a proposal which has been echoed by several international recommendations on neonatal resuscitation.…”
Section: Introductionmentioning
confidence: 99%
“…Some therapies such as surfactants and oxygen supplementation as adjutant and alternative therapy are used for lung development in preterm infants. Oxygen is the most commonly administered drug for infants with pathological conditions leading to tissue hypoxia (5). Oxygen delivery is adopted depending on the infant's needs and the type of disease.…”
Section: Introductionmentioning
confidence: 99%
“…Although oxygen therapy is the most common therapy used for infants, inappropriate control of administered oxygen could lead to irrevocable damage to many of the newborns, particularly preterm infants (5). As oxygen is considered as a drug, then required cautions with reference to pharmacotherapy principles should be used in its administration (7) and, as with any other drugs, its indications and complications, care practices in administration, and monitoring should receive much attention (8).…”
Section: Introductionmentioning
confidence: 99%
“…Such practices may be harmful. 35 Instead, oxygen saturation values should be monitored closely, with measures to increase oxygenation used only as needed to maintain SpO 2 within the target range.…”
Section: Stability Of the Saturation Signal In Clinical Settingsmentioning
confidence: 99%