Clinical Practice of Photodynamic Therapy for Non-Small Cell Lung Cancer in Different Scenarios: Who Is the Better Candidate?

Abstract

Background: Photodynamic therapy (PDT) is a relatively safe and highly selectivity anti-tumor treatment, which might be increasingly used as a supplement to conventional therapies. A clinical overview and detailed comparison of how to select patients and lesions for PDT in different scenarios is urgently needed to provide a basis for clinical treatment. Summary: This review demonstrates the highlights and obstacles of applying PDT for lung cancer, and underlines points worth considering when planning to initiate PDT. The aim is to make out the appropriate selection and help PDT develop efficacy and precision through a better understanding of its clinical use. Key Messages: ● Increasing evidence supports the feasibility and safety of Photodynamic therapy (PDT) in the treatment of NSCLC. ● It is important to recognize the factors that influence the efficacy of PDT to develop individualized management strategies and implement well-designed procedures. ● These important issues should be worth considering in the present and further research.