Clinical practice guideline exercise and lifestyle in chronic kidney disease

Baker, Luke A.; March, Daniel S.; Wilkinson, Thomas J.; Billany, Roseanne E; Bishop, Nicolette C.; Castle, Ellen M.; Chilcot, Joseph; Davies, Mark D.; Graham-Brown, Matthew; Greenwood, Sharlene; Junglee, Naushad A.; Kanavaki, Archontissa M.; Lightfoot, Courtney J; Macdonald, Jamie; Rossetti, Gabriella; Smith, Alice C.; Burton, James O.

doi:10.1186/s12882-021-02618-1

Cited by 101 publications

(87 citation statements)

References 244 publications

(332 reference statements)

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“…Increasing physical activity levels may lead to improved physical function and, in turn, maintenance of independence and improved survival rates in patients with CKD ( 7 ). Therefore, most guidelines recommend 150 min of moderate intensity physical activity per week for CKD ( 21 , 22 ). However, this recommendation is based on results from the general population, and the level of physical activity that would benefit people with chronic disease who have CKD is still unknown.…”

Section: Discussionmentioning

confidence: 99%

Physical Activity and Mortality in Patients With Chronic Kidney Disease: A Protocol for Systematic Review and Dose-Response Meta-Analysis

et al. 2022

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ObjectiveTo examine the dose-response associations between total physical activity, different intensity of physical activity, and all-cause mortality in patients with chronic kidney disease (CKD).Methods and AnalysisPubMed, Embase, Web of Science, and the Cochrane library will be searched from inception to June 2022. Only cohort studies assessing physical activity associations with all-cause mortality among CKD patients will be considered for inclusion. The quality of included cohort studies will be evaluated according to the Newcastle-Ottawa Scale (NOS). The robust error meta-regression (REMR) model will be used to establish dose-response relationships between physical activity and mortality. Additional statistical analysis including Egger's test, subgroup analysis, sensitivity analysis. The strengths of evidence will be evaluated with the Grading of Recommendation, Assessment, Development, and Evaluation approach.Ethics and DisseminationEthics approval is not required as no private information from individuals is collected.PROSPERO Registration NumberCRD 42021283630.

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Section: Discussionmentioning

confidence: 99%

Physical Activity and Mortality in Patients With Chronic Kidney Disease: A Protocol for Systematic Review and Dose-Response Meta-Analysis

et al. 2022

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“…While 34% of CKD stage 1 to 2 patients were physically active, only 11% of CKD stage 5, 6% of HD patients, and 8% of PD patients were physically active in the same study [75]. Physical inactivity is one of the causes of a high symptom burden and leads to a loss of muscle mass and strength with a consequent functional decline, disability, poor QoL, and mortality [76].…”

Section: Exercisementioning

confidence: 91%

Healthy aging and chronic kidney disease

Merchant

Vathsala

2022

Kidney Res Clin Pract

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The world population is aging and the prevalence of noncommunicable diseases such as chronic kidney disease (CKD) will increase significantly. With advances in medical treatment and public health, the human lifespan continues to outpace the health span and the last decade of life is generally spent in poor health. In 2015, the World Health Organization defined healthy aging as 'the process of developing and maintaining the functional ability that enables wellbeing in older age.' CKD is increasingly being recognized as a model of accelerated aging and is associated with physical performance decline, cognitive decline, falls and fractures, poor quality of life, loss of appetite, and inflammation. Frailty and dementia are the final pathways and key determinants of disability and mortality independent of underlying disease. CKD, dementia, and frailty share a triangular relationship with synergistic actions and have common risk factors wherein CKD accelerates frailty and dementia through mechanisms such as uremic toxicity, metabolic acidosis and derangements, anorexia and malnutrition, dialysis-related hemodynamic instability, and sleep disturbance. Frailty accelerates glomerular filtration decline as well as dialysis induction in CKD and more than doubles the mortality risk. Anorexia is one of the major causes of protein-energy malnutrition, which is also prevalent in the aging population and warrants screening. Healthcare systems across the world need to have a system in place for the prevention of CKD amongst high-risk older adults, focusing on screening for poor prognostic factors amongst patients with CKD such as frailty, poor appetite, and cognitive impairment and providing necessary person-centered interventions to reverse underlying factors that may contribute to poor outcomes.

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“…Aerobic exercise recommendations for people with CKD are presented in Table 2 [25,30]. Available data suggests aerobic exercise improves VO 2peak in patients with CKD, ESKD, and kidney transplant recipients [61,79,[86][87][88][89][90][91][92][93][94][95].…”

Section: Aerobic Exercisementioning

confidence: 99%

“…In a landmark study, Myers et al [29] reported that peak exercise capacity was the strongest predictor of risk of death among adults with and without CVD. Given the prevalence of CVD in CKD patients and limited treatment options targeting traditional and non-traditional CVD risk factors in this population, the incoroporation of physical activity and exercise into the care of CKD seems critical for improving patient outcomes [30,31]. Therefore, the purpose of this narrative review is to discuss the evidence of physical activity and exercise in CKD patients and the effects on cardiovascular outcomes and fitness.…”

Section: Introductionmentioning

confidence: 99%

Physical Activity and Exercise for Cardiorespiratory Health and Fitness in Chronic Kidney Disease

Gollie¹,

Cohen²,

Patel³

2022

Rev. Cardiovasc. Med.

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Chronic kidney disease (CKD) is associated with an increased risk for cardiovascular disease (CVD), major adverse CVD events, and cardiovascular mortality. Low levels of physical activity and reduced cardiorespiratory fitness further compound the health consequences in this patient population. Aerobic exercise alone and the combination of aerobic and resistance exercise have beneficial effects for improving aerobic capacity while resistance exercise alone improves strength and skeletal muscle health. Given the prevalence of CVD in CKD patients and limited treatment options targeting traditional and non-traditional CVD risk factors in this population, the incoroporation of physical activity and exercise into the care of CKD seems critical for improving patient outcomes. Therefore, the purpose of this narrative review is to discuss the evidence of physical activity and exercise in CKD patients and the effects on cardiovascular outcomes and fitness.

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Clinical practice guideline exercise and lifestyle in chronic kidney disease

Cited by 101 publications

References 244 publications

Physical Activity and Mortality in Patients With Chronic Kidney Disease: A Protocol for Systematic Review and Dose-Response Meta-Analysis

Physical Activity and Mortality in Patients With Chronic Kidney Disease: A Protocol for Systematic Review and Dose-Response Meta-Analysis

Healthy aging and chronic kidney disease

Physical Activity and Exercise for Cardiorespiratory Health and Fitness in Chronic Kidney Disease

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