1979
DOI: 10.1002/j.1552-4604.1979.tb02507.x
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Clinical Pharmacology of Sodium Cellulose Phosphate

Abstract: The safety and effectiveness of sodium cellulose phosphate (SCP) in the treatment of calcium urolithiasis of absorptive hypercalciuria was explored. Eighteen patients with absorptive hypercalciuria with intestinal hyperabsorption of calcium, normal or suppressed parathyroid function, and active stone disease received 10 to 15 Gm SCP daily (2.5 to 5 Gm with meals) and 2 to 3 Gm magnesium gluconate daily (1 to 1.5 Gm twice daily orally separately from SCP) for eight to 54 months, while maintained on a moderate c… Show more

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Cited by 26 publications
(7 citation statements)
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“…Cellulose phosphate is a non-absorbable resin that binds calcium with high affinity thereby inhibiting intestinal absorption. Cellulose phosphate has advantages over both prednisolone and calcitonin in that it is administered orally and has minimal side effects [17]. Cellulose phosphate was used in seven children (64%) in this series, was well tolerated, and was not associated with any significant adverse effects.…”
Section: Discussionmentioning
confidence: 94%
“…Cellulose phosphate is a non-absorbable resin that binds calcium with high affinity thereby inhibiting intestinal absorption. Cellulose phosphate has advantages over both prednisolone and calcitonin in that it is administered orally and has minimal side effects [17]. Cellulose phosphate was used in seven children (64%) in this series, was well tolerated, and was not associated with any significant adverse effects.…”
Section: Discussionmentioning
confidence: 94%
“…19 In this study cellulose phosphate, in addition to chlorothiazide, was effective in restoring the elevated urinary calcium excretion to normal in all patients. Potential side effects include reduction of intestinal calcium absorption below normal, hypermagnesuria, and hyperoxaluria.…”
Section: Discussionmentioning
confidence: 65%
“…19 to Response to treatment with chlorothiazide and cellulose phosphate is seen in Figure 2. 19 to Response to treatment with chlorothiazide and cellulose phosphate is seen in Figure 2.…”
Section: Resultsmentioning
confidence: 99%
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“…This disorder commonly results in painful kidney stones. Sodium cellulose phosphate has been used to complex the calcium ions and thus remove them from the patient and minimize the risk of stone formation (50)(51)(52)(53)(54).…”
Section: Membrane Applications Cellulose Esters Are Effective In Memmentioning
confidence: 99%