Clinical pharmacokinetics: perceptions of hospital pharmacists in Qatar about how it was taught and how it is applied

Kheir, Nadir; Awaisu, Ahmed; Gad, Hoda; Elazzazy, Shereen; Jibril, Farah; Gajam, Mawadda

doi:10.1007/s11096-015-0183-3

Cited by 15 publications

(39 citation statements)

References 22 publications

(30 reference statements)

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“…The identification of areas of improvement in routine vancomycin TDM practices serves as an invaluable tool in guiding practitioners, policymakers, health care administrators, and researchers to devise ways of optimizing vancomycin TDM service utilization, minimizing costs of vancomycin therapy, and improving overall therapeutic outcomes. In Qatar, most of the clinicians are expatriates originating from the MENA region and Asia, suggesting that similar practices may be observed in other unexplored MENA countries. Thus, our findings will contribute to improving health care system efficiency and service quality through decreasing personnel time utilization and minimizing wastage of analytical resources in the MENA region.…”

Section: Discussionmentioning

confidence: 86%

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Vancomycin therapeutic drug monitoring service quality indices and clinical effectiveness outcomes: A retrospective cohort and clinical audit

Al-Sulaiti

Nader

Elmekaty

et al. 2020

J Am Coll Clin Pharm

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Introduction:Vancomycin is commonly used for the treatment of complicated infections caused by methicillin-resistant Staphylococcus aureus. The impact of vancomycin therapeutic drug monitoring (TDM) quality indices on clinical outcomes has not been previously explored.Objectives: This study aims to relate routine vancomycin TDM service quality indices to clinical effectiveness outcomes and to develop a pragmatic vancomycin-specific TDM quality assessment tool that can be used in quality audits.Methods: A retrospective chart review was conducted on adult non-dialysis vancomycin TDM records documented between January 2014 and October 2016 in three tertiary care hospitals under Hamad Medical Corporation (HMC) in Qatar. Evidencebased criteria and pilot-testing were applied to develop a quality assessment tool.The appropriateness of vancomycin TDM service and clinical outcomes were simultaneously evaluated.Results: A 13-criterion vancomycin TDM quality assessment tool was developed and used to evaluate 208 TDM records involving 99 patients. The indications for TDM requests were judged appropriate in 77.4% (n = 161) of the records. However, most of the blood samples were deemed to be incorrectly timed (70.7%, n = 147). Inappropriate vancomycin TDM practices compared with appropriate practices were associated with lower therapeutic cure (47.3% vs 75%, P-value = .009).Conclusions: Vancomycin TDM requests were justified at HMC. However, inappropriate practices were associated with suboptimal clinical outcomes, signifying the importance of routine quality audits using rigorous evaluation tools. The developed tool can be used to determine setting-specific deficiencies in routine vancomycin TDM practices.

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Section: Discussionmentioning

confidence: 86%

“…TDM service in Qatar is largely influenced and undertaken by a different cadre of health care professionals who are mostly expatriates. The expatriates are mostly from Asian and MENA educational and clinical training backgrounds . This makes the TDM clinical practice setting in Qatar representative and generalizable to the MENA region.…”

Section: Introductionmentioning

confidence: 99%

Vancomycin therapeutic drug monitoring service quality indices and clinical effectiveness outcomes: A retrospective cohort and clinical audit

Al-Sulaiti

Nader

Elmekaty

et al. 2020

J Am Coll Clin Pharm

Self Cite

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“…The results almost lower than what reported by another study, because the pharmacokinetic services established well developed than the site of the study research. [10] In many instances, healthcare systems and organizations are not optimally collaborating with academic institutions. Several opportunities exist to optimize the partnership between academic institutes with the hospital.…”

Section: Answered Question 43mentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9] However, to the best of our knowledge, there are no studies conducted on the perception, feeling and attitude of the CPSs or on barriers of pharmacokinetic service implementations in the Gulf or Middle Eastern countries or in other countries. [10] Therefore, in this study, we aimed to explore the pharmacist's perception of barriers of implementation of pharmacokinetic services at MOH hospitals in Saudi Arabia.…”

Section: Introductionmentioning

confidence: 99%

National Survey of Pharmacokinetic Services in Saudi Arabia: Perceptions and Barriers of Service Implementations

Alomi¹,

Aldosary²,

Elshenawy³

2019

IJPCS

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Objectives: To explore the pharmacokinetic services at the Ministry of Health (MOH) hospitals in Saudi Arabia with an emphasis on perceptions and barriers of service implementation. Methods: This is a 2-month cross-sectional national survey of pharmacokinetic services with a focus on pharmacy management and resources at MOH hospitals in Saudi Arabia. The study consisted of two parts: the first part collected demographic information and the second part consisted of 43 questions divided into three domains. The questions were derived from the American Society of Health-System Pharmacists (ASHP) guidelines and from the literature. We used 5-point Likert response scale system with close-ended questions to obtain responses. An electronic questionnaire was distributed to the coordinators of the clinical pharmacy services or drug information centers at MOH hospitals and it analyzed the perceptions and barriers of pharmacokinetic service implementations section through the Survey Monkey system. Results: A total of 43 hospital pharmacies responded to the questionnaire, with the response rate of 86%. The majority of pharmacokinetic services were provided to the adult patients (37 (86.05%)) followed by the pediatric and geriatric patients (19 (44.19%) and 13 (30.23%), respectively) with most of the responding hospitals having less than 20 beds (23 (53.5%)). The categories with most of the barriers of pharmacokinetic service implementation were lack of knowledge (20 (64.52%)), lack of pharmacokinetic education (16 (51.61%)) and lack of an expert pharmacist in pharmacokinetic services (16 (51.61%)). Most of the responders agreed that clinical pharmacokinetic services were necessary for hospitals (23 (53.5%)). The responders agreed that the clinical pharmacist through pharmacokinetic services had a positive financial impact and cost avoidance on healthcare system (23 (53.5%)). Most of the responders stated that pharmacokinetic services improve the safety and efficacy of patient care (33 (89.2%)). Most of the responders agreed that the pharmacokinetic services improved patients' clinical outcome (33 (89.2%)) and prevented drug-related problems (33 (89.2%)), whereas few of the pharmacokinetic services were provided only 10 (29.4%) over 24 hr per day. Conclusion: Despite the positive attitude of hospital management toward pharmacokinetic services, there was a lack of education and training regarding the same at MOH hospitals in Saudi Arabia. Revision of strategic planning of pharmacokinetic services with regard to their improvement and implementation are required at all MOH hospitals in Saudi Arabia.

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“…It included general pharmacokinetic practice, medication monitored, cost avoidance and perception toward of the services. [3][4][5][6][7] Monitoring of drug therapy including workload analysis of pharmacokinetics and documentation does not occur in most of the literature. Also, the pharmacokinetics education and training were not included in most of the published survey in the worldwide and Gulf or Middle East countries.…”

Section: Introductionmentioning

confidence: 99%

National Survey of the Pharmacokinetics Services at the Ministry of Health Hospitals in Saudi Arabia: Drug Therapy Monitoring and Healthcare Professional Education

Alomi¹,

Elshenawy²,

Al-Jarallah³

2019

IJPCS

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Objectives: A clinical pharmacist offers vital support in the expansion of a final prescription with improved patient management and enhanced safety. The aim of the current study to explore the Pharmacokinetics services at Ministry of Health (MOH) hospitals in Saudi Arabia with an emphasis on drug therapy monitoring and patient's education. Methods: This is a 2-months cross-sectional national survey related to the Pharmacokinetics services with a focus on drug therapy monitoring and education of pharmacist at MOH hospitals in Saudi Arabia. The study consisted of two parts; the first part captures demographic information and the second part contained 43 questions designed by the authors. It was derived from American Society of Health-System Pharmacists (ASHP) guidelines and from the literature. We used the 5-point Likert response scale system to obtain responses of the participants; there were close-ended questions. The electronic questionnaire was distributed to all the coordinators of the clinical pharmacy services or to the drug information centers at MOH hospitals. All analysis was done through survey monkey system. Results: A total of 43 hospital pharmacies returned the survey, for a response rate of 86%. The most clinical pharmacokinetics services documented were drug quality reporting 34 (87.18%), drug information inquiries 35 (83.33%), adverse drug reaction 35 (81.40%) and medication error 35 (81.40%). Highest clinical impact and cost avoidance of clinical Pharmacokinetics services were drug information inquiries 25 (60.98%), the drug quality reporting system 21 (53.85%) and pharmacist intervention 21 (52.5%). Analysis of monthly workload for clinical Pharmacokinetics services were a number of drug information inquiries 28 (70%) and the number of prescriptions needs 25 (64.1%). The clinical Pharmacokinetics services education and training for pharmacists were found at average 7.8 (20.89%) hospitals with high percentages type of educations was short education course 1-5 days [15 (39.47%)] and long training course 4-5 weeks [8 (21.05%)]. While Pharmacokinetics services education and training for healthcare provider were found at main 6 (15.66%) hospitals only with high percentages type of educations was short education course 1-5 days [8 (20.00%)] and Pharmacokinetics competencies 7 (18.92%). Conclusion: Pharmacokinetics services on drug therapy monitoring was not competent at half MOH hospital, while only few of the hospitals had pharmacokinetics education and training to offer. Implementing the MOH pharmacokinetics services strategy with an emphasis on the drug therapy monitoring with education and training is required at all MOH hospitals in Saudi Arabia.

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Clinical pharmacokinetics: perceptions of hospital pharmacists in Qatar about how it was taught and how it is applied

Abstract: PK course contents were perceived to lack depth and relevance to practice, and pharmacist had no experiential training that included aspects of PK. These, and other issues, result in poor application of PK in practice.

Cited by 15 publications

References 22 publications

Vancomycin therapeutic drug monitoring service quality indices and clinical effectiveness outcomes: A retrospective cohort and clinical audit

Vancomycin therapeutic drug monitoring service quality indices and clinical effectiveness outcomes: A retrospective cohort and clinical audit

National Survey of Pharmacokinetic Services in Saudi Arabia: Perceptions and Barriers of Service Implementations

National Survey of the Pharmacokinetics Services at the Ministry of Health Hospitals in Saudi Arabia: Drug Therapy Monitoring and Healthcare Professional Education

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