Clinical Pattern and Therapeutic Results Achieved in 1490 Patients with Germ-Cell Tumours of the Testis: the Experience of the Spanish Germ-Cell Cancer Group (GG)

Germà-Lluch, J. R.; Muro, Xavier García del; Maroto, Pablo; Paz‐Ares, Luis; Arranz, José Ángel; Gumà, Josep; Alba, Emilio; Sastre, Javier; Aparicio, Jorge; Fernández, Antonio; Barnadas, Agustí; Terrassa, J.; Saenz, A.; Almenar, D.; López‐Brea, Marta; Climent, Miguel Ángel; Sánchez, Miguel Ángel Goenaga; Vega, Rosalba; Berenguer, G.; Pérez, Xavier

doi:10.1016/s0302-2838(02)00439-6

Cited by 126 publications

(80 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The grouping of histological subdiagnoses differs between reported series. However, our finding that the majority (87%) of patients had either pure embryonal carcinoma or mixed tumours, was consistent with previous reports [16,17]. Reported vascular invasion in 45 Á/50% of NSGCT [4,17], is in agreement with our data.…”

Section: Discussionsupporting

confidence: 94%

Patients with non-seminoma germ cell tumours treated in a minor oncology department: the importance of multi-institutional protocols and research collaboration

et al. 2005

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 94%

Patients with non-seminoma germ cell tumours treated in a minor oncology department: the importance of multi-institutional protocols and research collaboration

et al. 2005

View full text Add to dashboard Cite

show abstract

“…[13][14][15][16][17][18][19][20] The data in these series are now mature and relapse rates have consistently been reported to be about 15% in unselected patients with stage I disease. The predominant site of relapse in all studies was in the paraaortic lymph nodes; 41 of 49 (82%) of relapses in the Danish Testicular Cancer Study Group (DATECA) study and 57 of 64 (85%) in the Princess Margaret Hospital (PMH) series.…”

Section: Surveillancementioning

confidence: 99%

Canadian consensus guidelines for the management of testicular germ cell cancer

Wood

Kollmannsberger

Jewett

et al. 2013

CUAJ

123

View full text Add to dashboard Cite

“…Nustatyta, kad išsamiau ištyrus pacientą su minėtu nusiskundimu, net iki 50 proc. atvejų randamas sėklidės vėžys [16]. Apie 20 proc.…”

Section: Diskusijaunclassified

Sėklidės vėžio kombinuoto gydymo analizė

Žalimas

Kindurys

Platkevičius

et al. 2015

Medicinos Teorija Ir Praktika

View full text Add to dashboard Cite

Santrauka dešinioji -20 (45,5 proc.). Po operacijos 14 (32 proc.) pacientų histologiškai nustatyta sėklidės seminominis, 30 (68 proc.) -neseminominis germinacinių ląstelių navikas. Pagal Tarptautinės urologų asociacijos gairių siūlomą vertinimą ("International Germ Cell Cancer Collaborative Group"): geros prognozės -26 ligoniai (59 proc.), vidutinės -13 (30 proc.), blogos -5 (11 proc.). Didelių dozių chemoterapija su autologine kamieninių kraujo ląstelių transplantacija taikyta 9 (20,5 proc.) pacientams, kurie buvo blogoje prognostinėje grupėje, ir pacientams, kuriem po pradinės chemoterapijos pastebėtas ligos progresavimas. Po chemoterapijos dėl nustatytų likutinių masių 2 (4,5 proc.) pacientams atlikta plaučio rezekcija, 2 (4,5 proc.) pašalinta smegenų metastazė, 23 (52 proc.) pašalinti pakitę regioniniai retroperitoniniai limfmazgiai, 1 (2,3 proc.) pašalinti pakitę neregioniniai viršraktikauliniai limfmazgiai, o 1 (2,3 proc.) taikytas spindulinis gydymas. Vidutinis stebėjimo laikotarpis 39,4 (± 27,8) mėnesio, per kurį 40 (91 proc.) pacientų buvo pasiekta remisija, 1 (2 proc.) ligoniui progresavimo požymių įvertinti negalime, kadangi nesikreipė, ir 3 (7 proc.) pastebėtas ligos progresavimas, iš jų 2 ligoniai mirė dėl vėžinės intoksikacijos, 1 pacientui šiuo metu taikoma chemoterapija. Bendras tiriamųjų 5 metų išgyvenamumas -96 proc. Išvados. Sėklidės vėžys yra dažniausias solidinis navikas tarp jaunų vyrų. Dėl neskausmingų ankstyvų simptomų ir vengimo kreiptis į gydytoją vėžys nustatomas vėlesnių stadijų su blogesne prognoze. abStract Key words: testicular cancer, germ cell tumor, cancer markers, prognostic groups. Objective. Evaluate treatment results of testicular cancer at Vilnius university hospital Santariskiu klinikos Urology center. Patients and methods. From 2004 till 2014 at Vilnius university hospital Santariskiu klinikos Urology center 53 patients were operated due to testicular cancer. 44 patients were selected to participate in this retrospective study. General characteristics (age, diagnosis, labaratory findings, applied treatment) were obtained from patient's case-record. Results. The median age was 30.48 (± 8.59) years. Most patients complained becouse of enlarged testicle -26 (59.1 %). All patients underwent high orchofuniculectomy: 24 (59.1) -left side, 20 (45.5 %) -right side. Testicular seminoma and nonseminoma cancer on postoperative histological examination accounted for 14 (32 %) and 30 (68 %), respectively. According to International Germ Cell Cancer Collaborative Group suggested prognostic evaluation we distributed our patients into prognostic groups: 26 (59 %) -good, 13 (30 %) -intermediate and 5 (11 %) patients with poor prognosis. Due to disease progression after primary chemotherapy or poor prognosis 9 (20.5 %) patients underwent high-dose chemotherapy with autologous blood stem cell transplantation. Due to remaining post-chemotherapic abnormal masses 23 (52 %) patients had regional retroperitoneal lymph nodes dissected, 1 (2.3 %) abnormal non-regional supraclavicular lymph node wa...

show abstract

Clinical Pattern and Therapeutic Results Achieved in 1490 Patients with Germ-Cell Tumours of the Testis: the Experience of the Spanish Germ-Cell Cancer Group (GG)

Cited by 126 publications

References 19 publications

Patients with non-seminoma germ cell tumours treated in a minor oncology department: the importance of multi-institutional protocols and research collaboration

Patients with non-seminoma germ cell tumours treated in a minor oncology department: the importance of multi-institutional protocols and research collaboration

Canadian consensus guidelines for the management of testicular germ cell cancer

Sėklidės vėžio kombinuoto gydymo analizė

Contact Info

Product

Resources

About