“…[58][59][60] Adults have highly variable, although generally low, immunoglobulin concentrations, with concentrations ranging from 127 to 3969 mg/dL in one study; most have γ-globulin fractions of less than 1 g/dL, which is lower than those of most ruminants. 53,61 Conditions associated with hypoimmunoglobulinemia beyond the neonatal period include the transition period between the waning of maternal immunoglobulin and the onset of vigorous endogenous production, protein-losing conditions in general, and immunodeficiency syndromes, including juvenile llama immunodeficiency syndrome (JLIDS). 62 When severe, it is best treated through administration of plasma.…”