Abstract:Acanthocheilonema (Dipetalonema) reconditum is a less pathogenic species of
filaria from the superfamily Filarioidea, and which parasitizes in the
subcutaneous connective tissue of dogs, hyenas and jackals. The results of
epidemiological studies indicate the zoonotic potential of A. reconditum,
bearing in mind it can cause infections with clinical disorders in humans.
This filaria is spread globally and it is mostly described in geographical
areas such as the Mediterranean Basin, the Middle E… Show more
“…In dogs, this disease has a cosmopolitan distribution, but it occurs mainly in tropical regions given the higher concentration and diversity of vectors in the tropics [2]. Some species in these families are considered to present little pathogenicity, but others may even cause death and present a zoonotic potential [3][4][5].…”
An 11-year-old male dog presenting exophthalmia and perforation of the cornea of the left eye was seen at the veterinary hospital of the State University of Maranhão. Upon physical examination, irregularly shaped granulomas of crumbly appearance were observed on the dog’s tongue. The dog was sent for ocular enucleation surgery. The following tests were requested: complete blood count, serum biochemistry, hemoparasite investigation, chest X-Ray, echocardiogram, electrocardiogram, cytology and nodule histopathology. The blood count revealed neutrophilia, signs of anemia, increased total plasma protein and thrombocytopenia. Serum biochemistry and the imaging examinations showed normal results. The cytological examination on the tongue nodules showed microfilariae and the histopathological examination showed chronic glossitis. Polymerase chain reaction (PCR) and genetic sequencing were performed on a blood sample, which made it possible to identify the species Acanthocheilonema reconditum. This is the first record worldwide of the occurrence of microfilariae of A. reconditum on tongue nodules. This finding serves to alert dermatologists and dentists regarding the need for a differential diagnosis for types of oral cavity lesions of unknown etiological origin.
“…In dogs, this disease has a cosmopolitan distribution, but it occurs mainly in tropical regions given the higher concentration and diversity of vectors in the tropics [2]. Some species in these families are considered to present little pathogenicity, but others may even cause death and present a zoonotic potential [3][4][5].…”
An 11-year-old male dog presenting exophthalmia and perforation of the cornea of the left eye was seen at the veterinary hospital of the State University of Maranhão. Upon physical examination, irregularly shaped granulomas of crumbly appearance were observed on the dog’s tongue. The dog was sent for ocular enucleation surgery. The following tests were requested: complete blood count, serum biochemistry, hemoparasite investigation, chest X-Ray, echocardiogram, electrocardiogram, cytology and nodule histopathology. The blood count revealed neutrophilia, signs of anemia, increased total plasma protein and thrombocytopenia. Serum biochemistry and the imaging examinations showed normal results. The cytological examination on the tongue nodules showed microfilariae and the histopathological examination showed chronic glossitis. Polymerase chain reaction (PCR) and genetic sequencing were performed on a blood sample, which made it possible to identify the species Acanthocheilonema reconditum. This is the first record worldwide of the occurrence of microfilariae of A. reconditum on tongue nodules. This finding serves to alert dermatologists and dentists regarding the need for a differential diagnosis for types of oral cavity lesions of unknown etiological origin.
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