Clinical overview of venous thromboembolism

Schellack, Gustav; Modau, T; Schellack, Natalie

doi:10.4102/safp.v58i1.4373

Cited by 5 publications

(6 citation statements)

References 7 publications

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“…Qualitative/group models for VTE risk assessment These models assign a group of patients to broad risk categories that are linked to appropriate prophylaxis options for Table 1 Risk factors for venous thromboembolism. [1,5,10,[12][13][14]19,20]…”

Section: Overview Of Commonly Used Ramsmentioning

confidence: 99%

A review of venous thromboembolism risk assessment models for different patient populations: What we know and don’t!

Mehta

Bhave

2023

Medicine

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Venous thromboembolism (VTE) is a common cause of morbidity and mortality in hospitalized patients. Globally, it is also the third leading vascular disease, after myocardial infarction and stroke. The incidence of VTE is reportedly higher in Western countries than in Asian countries. However, recent reports suggest an increasing incidence of VTE in Asian countries, including India. Since VTE is largely a preventable disease, early identification of risk factors can lead to disease prevention or the adoption of appropriate prophylactic measures. To this end, several VTE risk assessment models (RAMs) have been developed and validated for different populations who are at risk of developing VTE, such as hospitalized patients with medical illness/surgical indication, patients with cancer, and pregnant women. Evidence indicates that the systematic use of RAMs improves prophylaxis rates and lowers the burden of VTE. Given the increasing burden of VTE in the Indian population and poor prophylaxis rates, the implementation of systematic RAMs in routine clinical practice might ameliorate the disease burden in the country. We have assessed the evidence-based utilities of available RAMs and have delineated the most common and suitable RAMs for different populations including coronavirus disease 2019 affected patients. This review depicts the current status of implementation and validation of RAMs in the Indian scenario. It also highlights the need for additional validation studies, improved awareness, and implementation of RAMs in clinical practice for lowering the burden of VTE.

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Section: Overview Of Commonly Used Ramsmentioning

confidence: 99%

A review of venous thromboembolism risk assessment models for different patient populations: What we know and don’t!

Mehta

Bhave

2023

Medicine

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“…Venous thromboembolism is an acute and potentially life-threatening disease with a risk of recurrence [ 15 ]. VTE can manifest as DVT and pulmonary embolism.…”

Section: Reviewmentioning

confidence: 99%

Comparison of the Efficacy and Safety of Aspirin and Low-Molecular-Weight Heparin in Patients With a Fracture: A Meta-Analysis

Nimerta,

Faisal,

Reyaz

et al. 2023

Cureus

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The aim of this study is to compare the efficacy and safety of aspirin and low-molecular-weight heparin (LMWH) in preventing thromboembolic events in patients with fractures. The present meta-analysis was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched EMBASE, PubMed, and EBSCO to find articles comparing aspirin and LMWH in patients with orthopedic trauma from inception to April 15, 2023. Limits were set to studies published in the English language only. Outcomes assessed in this meta-analysis included VTE and all-cause mortality. VTE can manifest as deep venous thrombosis (DVT) and pulmonary embolism. For safety analysis, rates of wound complication, infection, and bleeding complications were compared between the two study groups. A total of three studies were included in this meta-analysis enrolling 12884 patients. The study found no significant difference between the two groups in the risk of DVT and pulmonary embolism, and aspirin was non-inferior to LMWH for the prevention of all-cause mortality in patients. Additionally, no significant safety risk was associated with aspirin thromboprophylaxis. These findings suggest that inexpensive over-the-counter aspirin is as effective as LMWH in terms of safety and efficacy profile, making it a feasible option to consider in clinical practice.

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“…Without prophylaxis, DVT incidence rates have been seen to range from 40% to 60% (Rahman et al, 2020). Pulmonary embolism (PE) is mostly caused by deep vein thrombosis (DVT) (Schellack et al, 2016).…”

Section: )mentioning

confidence: 99%

Effect of Educational Program regarding Risk Assessment and preventive Strategies among Orthopedic Surgical Patients with Deep Vein Thrombosis

Mohamed Khalil,

Mohamed Ramadan Farag,

S. Abu Almakarem

et al. 2023

Egyptian Journal of Health Care

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Background: Deep Vein thrombosis (DVT) is thrombophlebitis of deep veins and is known to be associated with fatal complications. The use of appropriate measures through risk assessment is of vital importance in preventing DVT-related complications. Well's criteria are a beneficial tool in categorizing the patients and, therefore may guide in using appropriate preventive strategies and promoting the wellbeing of immobilized patients. The present study aimed to evaluate the effect of educational program regarding risk assessment and preventive strategies among orthopedic surgical patients with deep vein thrombosis. Research design: This study used a quasi-experimental research design. Setting: The study was carried out in the orthopedic department and orthopedic outpatient clinic at Qena General Hospital. Subjects: The samples were selected by a convenient sampling technique of all orthopedic surgical patients with deep vein thrombosis admitted to the above-mentioned settings at th e time of data collection. Tools: Three tools were used for data collection of this study: Tool I: Structure interview Sheet, Tool II: Observational checklist, and Tool III -Observational checklist for preventive strategies were used. Results: The findings of the study revealed that there were highly significant improvements in patient's knowledge regarding deep vein thrombosis post-educational program implementation (P=0.005). Statistical highly significant differences and reductions were detected between orthopedic surgical patients with deep vein thrombosis post-educational program implementation regarding risk assessment and preventive strategies. Conclusion: The educational program implementation had a significant positive effect on reducing risk assessment and preventing deep vein thrombosis among orthopedic surgical patients. Recommendations: The educational program regarding deep vein thrombosis prevention should be conducted and integrated into the rehabilitation programs. Provide the patients with booklets and illustrated pamphlets for each to improve their information and reduce their risk for deep vein thrombosis.

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Clinical overview of venous thromboembolism

Cited by 5 publications

References 7 publications

A review of venous thromboembolism risk assessment models for different patient populations: What we know and don’t!

A review of venous thromboembolism risk assessment models for different patient populations: What we know and don’t!

Comparison of the Efficacy and Safety of Aspirin and Low-Molecular-Weight Heparin in Patients With a Fracture: A Meta-Analysis

Effect of Educational Program regarding Risk Assessment and preventive Strategies among Orthopedic Surgical Patients with Deep Vein Thrombosis

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